Global Patent Index - EP 1043994 A4

EP 1043994 A4 20020911 - METHOD FOR TREATING MULTIPLE SCLEROSIS

Title (en)

METHOD FOR TREATING MULTIPLE SCLEROSIS

Title (de)

THERAPIE DER MULTIPLEN SKLEROSE

Title (fr)

METHODE DE TRAITEMENT DE LA SCLEROSE EN PLAQUES

Publication

EP 1043994 A4 20020911 (EN)

Application

EP 99900751 A 19990106

Priority

  • US 9900126 W 19990106
  • US 7067698 P 19980107

Abstract (en)

[origin: WO9934797A1] A method for treating multiple sclerosis comprising administering compounds of Formula (I) where X4 is a 1-substituted cyclohexyl group and the other groups are ethers or thioethers or a compound of Formula (II) where W is an aliphatic group of 2 to 6 carbons and R3 is an acid, amide or aromatic or heteroaromatic group and Z is exemplified by an alcohol or alcohol derivative.

IPC 1-7

A61K 31/41; A61K 31/235; A61K 31/165; A61K 31/075; A61K 31/19; A61K 31/215; A61K 31/38; A61K 31/425; A61K 31/44; A61K 31/505

IPC 8 full level

C07D 285/12 (2006.01); A61K 31/075 (2006.01); A61K 31/165 (2006.01); A61K 31/192 (2006.01); A61K 31/216 (2006.01); A61K 31/275 (2006.01); A61K 31/381 (2006.01); A61K 31/41 (2006.01); A61K 31/4245 (2006.01); A61K 31/426 (2006.01); A61K 31/433 (2006.01); A61K 31/4409 (2006.01); A61K 31/505 (2006.01); A61P 25/00 (2006.01); C07C 255/46 (2006.01); C07D 257/04 (2006.01); C07D 271/06 (2006.01); C07D 271/10 (2006.01)

CPC (source: EP)

A61K 31/075 (2013.01); A61K 31/165 (2013.01); A61K 31/192 (2013.01); A61K 31/216 (2013.01); A61K 31/381 (2013.01); A61K 31/41 (2013.01); A61K 31/4245 (2013.01); A61K 31/426 (2013.01); A61K 31/433 (2013.01); A61K 31/4409 (2013.01); A61K 31/505 (2013.01); A61P 25/00 (2017.12)

Citation (search report)

  • [Y] WO 9619990 A1 19960704 - SMITHKLINE BEECHAM CORP [US], et al
  • [Y] DATABASE MEDLINE [online] 1 August 1997 (1997-08-01), EKHOLM D ET AL: "Differential expression of cyclic nucleotide phosphodiesterase 3 and 4 activities in human T cell clones specific for myelin basic protein.", XP002205622, Database accession no. NLM9233651 & JOURNAL OF IMMUNOLOGY (BALTIMORE, MD.: 1950) UNITED STATES 1 AUG 1997, vol. 159, no. 3, 1 August 1997 (1997-08-01), pages 1520 - 1529, ISSN: 0022-1767
  • [Y] DATABASE MEDLINE [online] October 1997 (1997-10-01), SOMMER N ET AL: "Therapeutic potential of phosphodiesterase type 4 inhibition in chronic autoimmune demyelinating disease.", XP002205623, Database accession no. NLM9357447 & JOURNAL OF NEUROIMMUNOLOGY. NETHERLANDS OCT 1997, vol. 79, no. 1, October 1997 (1997-10-01), pages 54 - 61, ISSN: 0165-5728
  • See references of WO 9934797A1

Designated contracting state (EPC)

BE CH DE ES FR GB IT LI NL

DOCDB simple family (publication)

WO 9934797 A1 19990715; AU 2026299 A 19990726; CA 2317548 A1 19990715; EP 1043994 A1 20001018; EP 1043994 A4 20020911; JP 2002500187 A 20020108

DOCDB simple family (application)

US 9900126 W 19990106; AU 2026299 A 19990106; CA 2317548 A 19990106; EP 99900751 A 19990106; JP 2000527246 A 19990106