EP 1043994 A4 20020911 - METHOD FOR TREATING MULTIPLE SCLEROSIS
Title (en)
METHOD FOR TREATING MULTIPLE SCLEROSIS
Title (de)
THERAPIE DER MULTIPLEN SKLEROSE
Title (fr)
METHODE DE TRAITEMENT DE LA SCLEROSE EN PLAQUES
Publication
Application
Priority
- US 9900126 W 19990106
- US 7067698 P 19980107
Abstract (en)
[origin: WO9934797A1] A method for treating multiple sclerosis comprising administering compounds of Formula (I) where X4 is a 1-substituted cyclohexyl group and the other groups are ethers or thioethers or a compound of Formula (II) where W is an aliphatic group of 2 to 6 carbons and R3 is an acid, amide or aromatic or heteroaromatic group and Z is exemplified by an alcohol or alcohol derivative.
IPC 1-7
A61K 31/41; A61K 31/235; A61K 31/165; A61K 31/075; A61K 31/19; A61K 31/215; A61K 31/38; A61K 31/425; A61K 31/44; A61K 31/505
IPC 8 full level
C07D 285/12 (2006.01); A61K 31/075 (2006.01); A61K 31/165 (2006.01); A61K 31/192 (2006.01); A61K 31/216 (2006.01); A61K 31/275 (2006.01); A61K 31/381 (2006.01); A61K 31/41 (2006.01); A61K 31/4245 (2006.01); A61K 31/426 (2006.01); A61K 31/433 (2006.01); A61K 31/4409 (2006.01); A61K 31/505 (2006.01); A61P 25/00 (2006.01); C07C 255/46 (2006.01); C07D 257/04 (2006.01); C07D 271/06 (2006.01); C07D 271/10 (2006.01)
CPC (source: EP)
A61K 31/075 (2013.01); A61K 31/165 (2013.01); A61K 31/192 (2013.01); A61K 31/216 (2013.01); A61K 31/381 (2013.01); A61K 31/41 (2013.01); A61K 31/4245 (2013.01); A61K 31/426 (2013.01); A61K 31/433 (2013.01); A61K 31/4409 (2013.01); A61K 31/505 (2013.01); A61P 25/00 (2017.12)
Citation (search report)
- [Y] WO 9619990 A1 19960704 - SMITHKLINE BEECHAM CORP [US], et al
- [Y] DATABASE MEDLINE [online] 1 August 1997 (1997-08-01), EKHOLM D ET AL: "Differential expression of cyclic nucleotide phosphodiesterase 3 and 4 activities in human T cell clones specific for myelin basic protein.", XP002205622, Database accession no. NLM9233651 & JOURNAL OF IMMUNOLOGY (BALTIMORE, MD.: 1950) UNITED STATES 1 AUG 1997, vol. 159, no. 3, 1 August 1997 (1997-08-01), pages 1520 - 1529, ISSN: 0022-1767
- [Y] DATABASE MEDLINE [online] October 1997 (1997-10-01), SOMMER N ET AL: "Therapeutic potential of phosphodiesterase type 4 inhibition in chronic autoimmune demyelinating disease.", XP002205623, Database accession no. NLM9357447 & JOURNAL OF NEUROIMMUNOLOGY. NETHERLANDS OCT 1997, vol. 79, no. 1, October 1997 (1997-10-01), pages 54 - 61, ISSN: 0165-5728
- See references of WO 9934797A1
Designated contracting state (EPC)
BE CH DE ES FR GB IT LI NL
DOCDB simple family (publication)
WO 9934797 A1 19990715; AU 2026299 A 19990726; CA 2317548 A1 19990715; EP 1043994 A1 20001018; EP 1043994 A4 20020911; JP 2002500187 A 20020108
DOCDB simple family (application)
US 9900126 W 19990106; AU 2026299 A 19990106; CA 2317548 A 19990106; EP 99900751 A 19990106; JP 2000527246 A 19990106