Global Patent Index - EP 1044003 A4

EP 1044003 A4 2000-12-27 - COMPOSITIONS AND METHODS FOR USE IN ISCHEMIA-REPERFUSION AND ENDOTOXIN-RELATED TISSUE INJURY

Title (en)

COMPOSITIONS AND METHODS FOR USE IN ISCHEMIA-REPERFUSION AND ENDOTOXIN-RELATED TISSUE INJURY

Title (de)

ZUSAMMENSTELLUNGEN UND METHODEN ZUR VERWENDUNG IN ISCHEMIE-REPERFUSIONS UND ENDOTOXINABHÄNGIGEN GEWEBESCHÄDEN

Title (fr)

COMPOSITIONS ET TRAITEMENTS CONVENANT POUR LES LESIONS TISSULAIRES LIEES A LA REPERFUSION D'UNE ISCHEMIE OU DUES A DES ENDOTOXINES

Publication

EP 1044003 A4 (EN)

Application

EP 98966091 A

Priority

  • US 9827600 W
  • US 493898 A

Abstract (en)

[origin: WO9934803A1] Methods of preventing or treating ischemia-reperfusion injury in an organ by administration of a composition containing a selective A1 adenosine receptor antagonist and/or a P2X purinoceptor antagonist are provided. Methods of preventing or treating endotoxin-related tissue injury by administration of a composition containing a selective A1 adenosine receptor antagonist and/or a P2X purinoceptor antagonist are also provided.

IPC 1-7 (main, further and additional classification)

A61K 39/395; A61K 31/435; A61K 31/44; A61K 31/505; A61K 31/515; A61K 31/52

IPC 8 full level (invention and additional information)

A61K 31/435 (2006.01); A61K 31/44 (2006.01); A61K 31/505 (2006.01); A61K 31/515 (2006.01); A61K 31/52 (2006.01); A61K 39/395 (2006.01)

CPC (invention and additional information)

A61K 31/661 (2013.01); A61K 31/522 (2013.01)

Citation (search report)

  • [X] WO 9526728 A1 19951012 - UNIV PENNSYLVANIA [US], et al
  • [A] WO 9737667 A1 19971016 - US HEALTH [US], et al
  • [A] WO 9533048 A2 19951207 - GLAXO GROUP LTD [GB], et al
  • [X] A. GASPARDONE ET AL.: "Effect of bamiphylline (a selective antagonist of A1-adenosine receptors) on exercise-induced myocardial ischemia.", JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, vol. 19, no. 3 suppl. A, 1 March 1992 (1992-03-01), USA, pages 60A, XP002119631
  • [A] J. SALMON ET AL.: "Human mononuclear phagocytes express adenosine A1 receptors.", THE JOURNAL OF IMMUNOLOGY, vol. 151, no. 5, 1 September 1993 (1993-09-01), Baltimore, MD, USA, pages 2775 - 2785, XP002151628
  • [A] H. KU ET AL.: "Monoclonal antibodies to adenosine receptor by an auto-anti-idiotypic approach.", THE JOURNAL OF IMMUNOLOGY, vol. 139, no. 7, 1 October 1987 (1987-10-01), Baltimore, MD, USA, pages 2376 - 2384, XP002151629
  • See also references of WO 9934803A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9934803 A1 19990715; AU 2206999 A 19990726; CA 2312867 A1 19990715; EP 1044003 A1 20001018; EP 1044003 A4 20001227

INPADOC legal status


2004-01-07 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20030701

2000-12-27 [A4] SUPPLEMENTARY SEARCH REPORT

- Effective date: 20001113

2000-12-27 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A4

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2000-12-20 [RIC1] CLASSIFICATION (CORRECTION)

- Free text: 7A 61K 39/395 A, 7A 61K 31/52 B, 7A 61K 31/435 B, 7A 61K 31/515 B, 7A 61K 31/505 B, 7A 61K 31/44 B

2000-10-18 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000807

2000-10-18 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE