Global Patent Index - EP 1045697 A2

EP 1045697 A2 2000-10-25 - EXTENSION OF CELLULAR LIFESPAN, METHODS AND REAGENTS

Title (en)

EXTENSION OF CELLULAR LIFESPAN, METHODS AND REAGENTS

Title (de)

ZELLLEBENSDAUERVERLÄNGERUNG, MEHODEN UND REAGENZIEN

Title (fr)

ALLONGEMENT DE LA DUREE DE VIE D'UNE CELLULE, ET PROCEDES ET REACTIFS ASSOCIES

Publication

EP 1045697 A2 (EN)

Application

EP 99903059 A

Priority

  • US 9900682 W
  • US 7122098 P
  • US 7145598 P
  • US 6365798 A

Abstract (en)

[origin: WO9935243A2] The present invention relates to methods and reagents for extending the life-span, e.g., the number of mitotic divisions, of a cell. In general, the subject method relies on the ectopic expression of the telomerase catalytic subunit EST2, or a bioactive fragment thereof. The subject method is useful both in vivo, ex vivo and in situ.

IPC 1-7 (main, further and additional classification)

A61K 38/17; A61K 7/48; C12N 9/12

IPC 8 full level (invention and additional information)

C12N 15/09 (2006.01); A61K 8/00 (2006.01); A61K 8/64 (2006.01); A61K 8/96 (2006.01); A61K 31/7105 (2006.01); A61K 31/711 (2006.01); A61K 38/00 (2006.01); A61K 38/16 (2006.01); A61K 38/17 (2006.01); A61K 38/45 (2006.01); A61K 45/00 (2006.01); A61K 48/00 (2006.01); A61P 17/02 (2006.01); A61P 29/00 (2006.01); A61P 43/00 (2006.01); A61Q 17/00 (2006.01); C12N 5/06 (2006.01)

CPC (invention and additional information)

A61K 38/162 (2013.01); A61K 38/1709 (2013.01); A61K 38/45 (2013.01); A61K 48/00 (2013.01)

Citation (search report)

See references of WO 9935243A3

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9935243 A2 19990715; WO 9935243 A3 19990916; WO 9935243 A9 19991028; AU 2317299 A 19990726; AU 759437 B2 20030417; CA 2315265 A1 19990715; EP 1045697 A2 20001025; IL 137101 D0 20010614; JP 2002500040 A 20020108

INPADOC legal status


2003-05-07 [18W] WITHDRAWN

- Effective date: 20030313

2001-05-02 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20010314

2000-10-25 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000802

2000-10-25 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE