EP 1045699 A1 20001025 - GENETIC IMMUNIZATION WITH CO-DELIVERY OF NUCLEIC ACID AND CYTOKINES IN A SINGLE VEHICLE
Title (en)
GENETIC IMMUNIZATION WITH CO-DELIVERY OF NUCLEIC ACID AND CYTOKINES IN A SINGLE VEHICLE
Title (de)
GENETISCHE IMMUNISIERUNG DURCH GEMEINSAME VERABREICHUNG VON NUKLEINSÄUREN UND ZYTOKINEN IM EINEN EINZIGEN TRÄGER
Title (fr)
IMMUNISATION GENETIQUE PAR L'ADMINISTRATION CONJOINTE D'ACIDES NUCLEIQUES ET DE CYTOKINES DANS UN EXCIPIENT UNIQUE
Publication
Application
Priority
- US 9900860 W 19990115
- US 7174698 P 19980116
Abstract (en)
[origin: WO9936089A1] Coacervates of nucleic acids and a polycationic biopolymer are useful for delivery of genes encoding antigens to mammals. The expression of the antigens in the mammal induces an immune response to the antigen. Furthermore, encapsulation of either or both of the antigen protein and a cytokine enhance the immune response. Selection of cytokines can be used to manipulate the type of immune response which is induced.
IPC 1-7
IPC 8 full level
A61K 9/00 (2006.01); A61K 9/51 (2006.01); A61K 31/711 (2006.01); A61K 38/00 (2006.01); A61K 39/39 (2006.01); A61K 47/36 (2006.01); A61K 47/42 (2006.01); A61K 47/48 (2006.01); A61K 48/00 (2006.01); A61P 37/04 (2006.01)
CPC (source: EP)
A61K 9/5169 (2013.01); A61K 39/39 (2013.01); A61K 47/61 (2017.07); A61K 47/645 (2017.07); A61K 48/00 (2013.01); A61P 37/04 (2017.12); A61K 2039/55522 (2013.01); A61K 2039/55555 (2013.01)
Citation (search report)
See references of WO 9936089A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9936089 A1 19990722; AU 2117299 A 19990802; AU 743226 B2 20020124; CA 2318498 A1 19990722; EP 1045699 A1 20001025; JP 2002509116 A 20020326; NZ 505876 A 20021220
DOCDB simple family (application)
US 9900860 W 19990115; AU 2117299 A 19990115; CA 2318498 A 19990115; EP 99901486 A 19990115; JP 2000539862 A 19990115; NZ 50587699 A 19990115