EP 1045831 A1 20001025 - SOLID SUPPORTED SYNTHESIS OF HYDROXAMIC ACIDS
Title (en)
SOLID SUPPORTED SYNTHESIS OF HYDROXAMIC ACIDS
Title (de)
FESTTRÄGER SYNTHESE VON HYDROXAMSÄURE
Title (fr)
SYNTHESE D'ACIDES HYDROXAMIQUES SUR SUPPORT SOLIDE
Publication
Application
Priority
- IB 9802117 W 19981228
- US 7098098 P 19980109
Abstract (en)
[origin: WO9935126A1] The subject invention involves processes for making hydroxamic acid compounds using a solid-support resin having an oxime moiety as the linking moiety of the resin, comprising the steps of (a) treating the resin with a carboxylic acid compound, such that it is attached to the resin by a condensation reaction between the oxime and carboxyl moieties; (b) optionally modifying the side chain; (c) cleaving a product from the resin by treating with O-tert-butyldimethylsilylhydroxylamine; (d) optionally modifying the side chain; and (e) optionally treating the resulting O-TBS-protected material with acid to produce an unprotected hydroxamic acid compound.
IPC 1-7
IPC 8 full level
C07C 259/04 (2006.01); C07C 259/06 (2006.01); C07C 259/10 (2006.01); C07C 319/20 (2006.01); C07D 307/68 (2006.01); C07B 61/00 (2006.01); C07C 323/62 (2006.01)
CPC (source: EP)
C07C 259/06 (2013.01); C07C 259/10 (2013.01); C07C 319/20 (2013.01); C07D 307/68 (2013.01); C07B 2200/11 (2013.01); C40B 40/00 (2013.01)
Citation (search report)
See references of WO 9935126A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
WO 9935126 A1 19990715; AU 1502999 A 19990726; CA 2318487 A1 19990715; EP 1045831 A1 20001025; IL 137217 A0 20010724; JP 2002500216 A 20020108; NO 20003541 D0 20000710; NO 20003541 L 20000831
DOCDB simple family (application)
IB 9802117 W 19981228; AU 1502999 A 19981228; CA 2318487 A 19981228; EP 98959113 A 19981228; IL 13721798 A 19981228; JP 2000527528 A 19981228; NO 20003541 A 20000710