Global Patent Index - EP 1045831 A1

EP 1045831 A1 2000-10-25 - SOLID SUPPORTED SYNTHESIS OF HYDROXAMIC ACIDS

Title (en)

SOLID SUPPORTED SYNTHESIS OF HYDROXAMIC ACIDS

Title (de)

FESTTRÄGER SYNTHESE VON HYDROXAMSÄURE

Title (fr)

SYNTHESE D'ACIDES HYDROXAMIQUES SUR SUPPORT SOLIDE

Publication

EP 1045831 A1 (EN)

Application

EP 98959113 A

Priority

  • IB 9802117 W
  • US 7098098 P

Abstract (en)

[origin: WO9935126A1] The subject invention involves processes for making hydroxamic acid compounds using a solid-support resin having an oxime moiety as the linking moiety of the resin, comprising the steps of (a) treating the resin with a carboxylic acid compound, such that it is attached to the resin by a condensation reaction between the oxime and carboxyl moieties; (b) optionally modifying the side chain; (c) cleaving a product from the resin by treating with O-tert-butyldimethylsilylhydroxylamine; (d) optionally modifying the side chain; and (e) optionally treating the resulting O-TBS-protected material with acid to produce an unprotected hydroxamic acid compound.

IPC 1-7 (main, further and additional classification)

C07C 259/04

IPC 8 full level (invention and additional information)

C07C 259/04 (2006.01); C07C 259/06 (2006.01); C07C 259/10 (2006.01); C07C 319/20 (2006.01); C07D 307/68 (2006.01); C07B 61/00 (2006.01); C07C 323/62 (2006.01)

CPC (invention and additional information)

C07D 307/68 (2013.01); C07C 259/06 (2013.01); C07C 259/10 (2013.01); C07C 319/20 (2013.01); C07B 2200/11 (2013.01); C40B 40/00 (2013.01)

Combination set (CPC)

C07C 319/20 + C07C 323/62

Citation (search report)

See references of WO 9935126A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

EPO simple patent family

WO 9935126 A1 19990715; AU 1502999 A 19990726; CA 2318487 A1 19990715; EP 1045831 A1 20001025; IL 137217 D0 20010724; JP 2002500216 A 20020108; NO 20003541 A 20000831; NO 20003541 D0 20000710

INPADOC legal status


2007-08-03 [REG HK WD] APPLICATIONS WITHDRAWN, DEEMED TO BE WITHDRAWN, OR REFUSED AFTER PUBLICATION IN HONG KONG

- Document: HK 1032948

2003-03-19 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20020914

2002-06-19 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20020503

2000-10-25 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000731

2000-10-25 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE