Global Patent Index - EP 1045843 A1

EP 1045843 A1 20001025 - INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE

Title (en)

INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE

Title (de)

INHIBITOREN DER FARNESYL-PROTEIN-TRANSFERASE

Title (fr)

INHIBITEURS DE LA FARNESYL-PROTEINE TRANSFERASE

Publication

EP 1045843 A1 20001025 (EN)

Application

EP 98960545 A 19981130

Priority

  • US 9825352 W 19981130
  • US 98532097 A 19971204

Abstract (en)

[origin: CA2312366A1] The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemoterapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.

IPC 1-7

C07D 401/02; A61K 31/415; A61K 31/47

IPC 8 full level

A61K 31/415 (2006.01); A61K 31/47 (2006.01); C07D 235/30 (2006.01); C07D 401/02 (2006.01); C07D 401/06 (2006.01); C07D 403/06 (2006.01); C07D 471/04 (2006.01)

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

DOCDB simple family (publication)

AU 1612099 A 19990616; CA 2312366 A1 19990610; EP 1045843 A1 20001025; EP 1045843 A4 20011024

DOCDB simple family (application)

AU 1612099 A 19981130; CA 2312366 A 19981130; EP 98960545 A 19981130