Global Patent Index - EP 1045843 A1

EP 1045843 A1 2000-10-25 - INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE

Title (en)

INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE

Title (de)

INHIBITOREN DER FARNESYL-PROTEIN-TRANSFERASE

Title (fr)

INHIBITEURS DE LA FARNESYL-PROTEINE TRANSFERASE

Publication

EP 1045843 A1 (EN)

Application

EP 98960545 A

Priority

  • US 9825352 W
  • US 98532097 A

Abstract (en)

[origin: CA2312366A1] The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemoterapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.

IPC 1-7 (main, further and additional classification)

C07D 401/02; A61K 31/415; A61K 31/47

IPC 8 full level (invention and additional information)

A61K 31/415 (2006.01); A61K 31/47 (2006.01); C07D 235/30 (2006.01); C07D 401/02 (2006.01); C07D 401/06 (2006.01); C07D 403/06 (2006.01); C07D 471/04 (2006.01)

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

EPO simple patent family

AU 1612099 A 19990616; CA 2312366 A1 19990610; EP 1045843 A1 20001025; EP 1045843 A4 20011024

INPADOC legal status


2002-07-03 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20011129

2001-10-24 [A4] SUPPLEMENTARY SEARCH REPORT

- Effective date: 20010911

2001-10-24 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A4

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

2001-10-24 [RIC1] CLASSIFICATION (CORRECTION)

- Free text: 7C 07D 235/30 A, 7C 07D 471/04 B, 7C 07D 401/06 B, 7C 07D 403/06 B, 7A 61K 31/415 B, 7A 61K 31/47 B

2000-10-25 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000704

2000-10-25 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

2000-10-25 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Free text: AL PAYMENT 20000704;LT PAYMENT 20000704;LV PAYMENT 20000704;MK PAYMENT 20000704;RO PAYMENT 20000704;SI PAYMENT 20000704