Global Patent Index - EP 1045843 A4

EP 1045843 A4 20011024 - INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE

Title (en)

INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE

Title (de)

INHIBITOREN DER FARNESYL-PROTEIN-TRANSFERASE

Title (fr)

INHIBITEURS DE LA FARNESYL-PROTEINE TRANSFERASE

Publication

EP 1045843 A4 20011024 (EN)

Application

EP 98960545 A 19981130

Priority

  • US 9825352 W 19981130
  • US 98532097 A 19971204

Abstract (en)

[origin: CA2312366A1] The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemoterapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.

IPC 1-7

C07D 235/30; C07D 471/04; C07D 401/06; C07D 403/06; A61K 31/415; A61K 31/47

IPC 8 full level

A61K 31/415 (2006.01); A61K 31/47 (2006.01); C07D 235/30 (2006.01); C07D 401/02 (2006.01); C07D 401/06 (2006.01); C07D 403/06 (2006.01); C07D 471/04 (2006.01)

Citation (search report)

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

DOCDB simple family (publication)

AU 1612099 A 19990616; CA 2312366 A1 19990610; EP 1045843 A1 20001025; EP 1045843 A4 20011024

DOCDB simple family (application)

AU 1612099 A 19981130; CA 2312366 A 19981130; EP 98960545 A 19981130