Global Patent Index - EP 1045845 A1

EP 1045845 A1 2000-10-25 - N-OXIDES OF HETEROCYCLIC COMPOUNDS WITH TNF AND PDE-IV INHIBITING ACTIVITY

Title (en)

N-OXIDES OF HETEROCYCLIC COMPOUNDS WITH TNF AND PDE-IV INHIBITING ACTIVITY

Title (de)

N-OXIDE VON HETEROCYCLISCHEN VERBINDUNGEN MIT TNF UND PDE-IV HEMMENDER WIRKUNG

Title (fr)

N-OXYDES DE COMPOSES HETEROCYCLIQUES AVEC ACTIVITE INHIBITRICE DE TNF ET PDE-IV

Publication

EP 1045845 A1 (EN)

Application

EP 99954132 A

Priority

  • GB 9903628 W
  • GB 9824160 A

Abstract (en)

[origin: WO0026208A1] N-oxides of formula (i) wherein R1 is CH3, CH2F, CHF2 or CF3; R2 is CH3 or CF3; R3 is F, Cl, Br, CN or CH3; and R4 is H, F, Cl, Br, CN or CH3; and pharmaceutically-acceptable salts thereof, are useful as therapeutic agents, e.g. for the treatment of inflammatory diseases.

IPC 1-7 (main, further and additional classification)

C07D 401/12; A61K 31/47; A61P 11/06

IPC 8 full level (invention and additional information)

A61K 31/4709 (2006.01); A61P 1/00 (2006.01); A61P 1/04 (2006.01); A61P 3/10 (2006.01); A61P 9/00 (2006.01); A61P 11/00 (2006.01); A61P 11/06 (2006.01); A61P 11/08 (2006.01); A61P 13/12 (2006.01); A61P 17/00 (2006.01); A61P 17/06 (2006.01); A61P 19/02 (2006.01); A61P 19/08 (2006.01); A61P 19/10 (2006.01); A61P 21/00 (2006.01); A61P 25/16 (2006.01); A61P 25/24 (2006.01); A61P 25/28 (2006.01); A61P 27/02 (2006.01); A61P 27/16 (2006.01); A61P 29/00 (2006.01); A61P 31/04 (2006.01); A61P 31/10 (2006.01); A61P 31/18 (2006.01); A61P 33/06 (2006.01); A61P 35/02 (2006.01); A61P 37/00 (2006.01); A61P 37/02 (2006.01); A61P 37/08 (2006.01); A61P 43/00 (2006.01); C07D 401/12 (2006.01)

CPC (invention and additional information)

C07D 401/12 (2013.01)

Citation (search report)

See references of WO 0026208A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 0026208 A1 20000511; AR 021094 A1 20020612; AU 1057100 A 20000522; AU 735574 B2 20010712; BR 9906719 A 20001017; CA 2312430 A1 20000511; CN 1287555 A 20010314; CO 5160316 A1 20020530; EP 1045845 A1 20001025; GB 9824160 D0 19981230; HU 0100570 A2 20011028; HU 0100570 A3 20021228; IL 136398 D0 20010614; JP 2002528541 A 20020903; NO 20003439 A 20000703; NO 20003439 D0 20000703; NZ 504933 A 20011026; PE 12322000 A1 20001128; PL 341732 A1 20010507; RU 2205830 C2 20030610; SK 10082000 A3 20010118; TR 200001941 T1 20010122; TW 546296 B 20030811; ZA 200002604 B 20010528

INPADOC legal status


2007-06-08 [REG HK WD] APPLICATIONS WITHDRAWN, DEEMED TO BE WITHDRAWN, OR REFUSED AFTER PUBLICATION IN HONG KONG

- Document: HK 1029337

2004-09-15 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20040309

2003-10-15 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20030829

2003-01-29 [RAP1] TRANSFER OF RIGHTS OF AN EP PUBLISHED APPLICATION

- Owner name: DARWIN DISCOVERY LIMITED

2000-10-25 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000711

2000-10-25 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2000-10-25 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Free text: AL PAYMENT 20000711;LT PAYMENT 20000711;LV PAYMENT 20000711;MK PAYMENT 20000711;RO PAYMENT 20000711;SI PAYMENT 20000711