Global Patent Index - EP 1045862 A1

EP 1045862 A1 2000-10-25 - POLYPEPTIDES, DNA CODING THEREFOR, FORMULATIONS THEREOF, AND THEIR USE IN INHIBITING FACTOR XII ACTIVATION

Title (en)

POLYPEPTIDES, DNA CODING THEREFOR, FORMULATIONS THEREOF, AND THEIR USE IN INHIBITING FACTOR XII ACTIVATION

Title (de)

POLYPEPTIDE, DAFÜR KODIERENDE DNA, DIESE ENTHALTENDE ZUSAMMENSETZUNGEN, UND UND DEREN VERWENDUNG ZUR INHIBIERUNG VON FAKTOR XII AKTIVIERUNG

Title (fr)

POLYPEPTIDES, ADN LES CODANT, LEURS FORMULATIONS ET LEUR UTILISATION DANS L'INHIBITION DE L'ACTIVATION DU FACTEUR XII

Publication

EP 1045862 A1 (EN)

Application

EP 99901059 A

Priority

  • GB 9900147 W
  • GB 9800817 A

Abstract (en)

[origin: WO9936439A1] A polypeptide, derivable from a Haementeria leech, which polypeptide is suitable for inhibiting C1 esterase and/or factor XII activation is disclosed, together with a nucleic acid sequence encoding the polypeptide. The polypeptide may be used as a pharmaceutical formulation or in gene therapy to treat or prevent cardiovascular, inflammatory or auto-immune disorders.

IPC 1-7 (main, further and additional classification)

C07K 14/815; A61K 38/58; A61K 48/00; C12N 1/21; C12N 15/12; C12N 15/70

IPC 8 full level (invention and additional information)

C12N 15/09 (2006.01); A61K 35/62 (2006.01); A61K 38/00 (2006.01); A61K 38/55 (2006.01); A61K 48/00 (2006.01); A61P 7/02 (2006.01); A61P 9/00 (2006.01); A61P 9/10 (2006.01); A61P 29/00 (2006.01); A61P 37/02 (2006.01); A61P 43/00 (2006.01); C07K 14/81 (2006.01); C07K 14/815 (2006.01); C12N 1/21 (2006.01); C12N 15/12 (2006.01); C12P 21/02 (2006.01)

CPC (invention and additional information)

C07K 14/8121 (2013.01); C07K 14/811 (2013.01); C07K 14/815 (2013.01); A61K 38/00 (2013.01); A61K 48/00 (2013.01)

Citation (search report)

See references of WO 9936439A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI NL PT SE

EPO simple patent family

WO 9936439 A1 19990722; AU 2068599 A 19990802; CA 2318358 A1 19990722; EP 1045862 A1 20001025; GB 9800817 D0 19980311; JP 2002508953 A 20020326

INPADOC legal status


2002-06-12 [18W] WITHDRAWN

- Ref Legal Event Code: 18W

- Date of withdrawal: 20020417

2000-12-27 [RBV] DESIGNATED CONTRACTING STATES (CORRECTION):

- Ref Legal Event Code: RBV

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI NL PT SE

2000-10-25 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 20000728

2000-10-25 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI NL PT SE

2000-10-25 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Ref Legal Event Code: AX

- Free Format Text: AL PAYMENT 20000728;LT PAYMENT 20000728;LV PAYMENT 20000728;MK PAYMENT 20000728;RO PAYMENT 20000728;SI PAYMENT 20000728