EP 1047425 A1 20001102 - INTEGRIN RECEPTOR ANTAGONISTS
Title (en)
INTEGRIN RECEPTOR ANTAGONISTS
Title (de)
INTEGRINREZEPTOR ANTAGONISTEN
Title (fr)
ANTAGONISTES DU RECEPTEUR DE L'INTEGRINE
Publication
Application
Priority
- GB 9810182 A 19980513
- GB 9811283 A 19980526
- US 9826539 W 19981214
- US 6991097 P 19971217
- US 8325198 P 19980427
- US 9258898 P 19980713
Abstract (en)
[origin: WO9930709A1] The present invention relates to compounds and derivatives thereof, their synthesis, and their use as vitronectin receptor antagonists. More particularly, the compounds of the present invention are antagonists of the vitronectin receptors alpha v beta 3 and/or alpha v beta 5 and are useful for inhibiting bone resorption, treating and preventing osteoporosis, and inhibiting vascular restenosis, diabetic retinopathy, macular degeneration, angiogenesis, atherosclerosis, inflammation, viral disease, and tumor growth.
IPC 1-7
A61K 31/435; A61K 31/40; C07D 207/26; C07D 413/06; C07D 471/04; C07D 401/06
IPC 8 full level
A61K 31/40 (2006.01); A61K 31/4015 (2006.01); A61K 31/435 (2006.01); A61K 31/4375 (2006.01); A61K 31/66 (2006.01); A61K 45/06 (2006.01); A61P 9/00 (2006.01); A61P 9/10 (2006.01); A61P 19/08 (2006.01); A61P 19/10 (2006.01); A61P 27/02 (2006.01); A61P 29/00 (2006.01); A61P 31/12 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01); C07D 207/26 (2006.01); C07D 401/06 (2006.01); C07D 401/14 (2006.01); C07D 413/06 (2006.01); C07D 471/04 (2006.01); C07D 519/00 (2006.01)
CPC (source: EP)
A61K 31/66 (2013.01); A61K 45/06 (2013.01); A61P 9/00 (2017.12); A61P 9/10 (2017.12); A61P 19/08 (2017.12); A61P 19/10 (2017.12); A61P 27/02 (2017.12); A61P 29/00 (2017.12); A61P 31/12 (2017.12); A61P 35/00 (2017.12); A61P 43/00 (2017.12); C07D 401/14 (2013.01); C07D 471/04 (2013.01); C07D 519/00 (2013.01)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE
Designated extension state (EPC)
AL LT LV MK RO SI
DOCDB simple family (publication)
WO 9930709 A1 19990624; AU 1725799 A 19990705; AU 736026 B2 20010726; CA 2315370 A1 19990624; EP 1047425 A1 20001102; EP 1047425 A4 20090422; JP 2002508323 A 20020319
DOCDB simple family (application)
US 9826539 W 19981214; AU 1725799 A 19981214; CA 2315370 A 19981214; EP 98962096 A 19981214; JP 2000538692 A 19981214