EP 1047779 A2 20001102 - METHODS AND COMPOSITIONS TO ALTER TISSUE SUSCEPTIBILITY TO IMMUNE INJURY, TO PROGRAMMED CELL DEATH, AND TO CLEARANCE BY THE RETICULOENDOTHELIAL SYSTEM
Title (en)
METHODS AND COMPOSITIONS TO ALTER TISSUE SUSCEPTIBILITY TO IMMUNE INJURY, TO PROGRAMMED CELL DEATH, AND TO CLEARANCE BY THE RETICULOENDOTHELIAL SYSTEM
Title (de)
VERFAHREN UND ZUSAMMENSETZUNGEN ZUR ÄNDERUNG DER EMPFINDLICHKEIT VON GEWEBE ZU IMMUN-VERLETZUNGEN, PROGRAMMIERTER ZELLTOD, UND ABBAU DURCH DAS RETIKULOENDOTHELIALE SYSTEM
Title (fr)
METHODES ET COMPOSITIONS PERMETTANT DE MODIFIER LA SENSIBILITE DES TISSUS FACE AUX LESIONS IMMUNITAIRES, A LA MORT CELLULAIRE PROGRAMMEE ET A LA CLAIRANCE PAR LE SYSTEME RETICULO-ENDOTHELIAL
Publication
Application
Priority
- US 9901087 W 19990119
- US 7195098 P 19980120
Abstract (en)
[origin: WO9936536A2] A method for extending the viability of mammalian cells or tissues comprising the step of inhibiting the expression of native PL scramblase within the cell or tissue is disclosed. In another embodiment of the invention, a method of decreasing the viability, metastatic or invasive potential of cancer cells, cancerous tissue, or viral-infected cell by causing increased expression or activity of PL scramblase protein within the cell or tissue is disclosed.
IPC 1-7
C12N 15/12; C07K 14/47; C12N 15/11; A61K 38/17; A61K 31/70; C12Q 1/68; G01N 33/68; A61K 48/00
IPC 8 full level
C07K 14/47 (2006.01); C12N 15/12 (2006.01); A61K 38/00 (2006.01); A61K 48/00 (2006.01)
CPC (source: EP)
C07K 14/47 (2013.01); A61K 38/00 (2013.01); A61K 48/00 (2013.01)
Citation (search report)
See references of WO 9936536A2
Designated contracting state (EPC)
DE ES FR GB IT NL
DOCDB simple family (publication)
WO 9936536 A2 19990722; WO 9936536 A3 19991209; WO 9936536 A9 19991104; AU 2326299 A 19990802; EP 1047779 A2 20001102
DOCDB simple family (application)
US 9901087 W 19990119; AU 2326299 A 19990119; EP 99903179 A 19990119