Global Patent Index - EP 1049665 A1

EP 1049665 A1 20001108 - VLA-4 ANTAGONISTS

Title (en)

VLA-4 ANTAGONISTS

Title (de)

VLA-4-ANTAGONISTEN

Title (fr)

ANTAGONISTES D'ANTIGENE-4 D'ACTIVATION TRES TARDIVE (VLA-4)

Publication

EP 1049665 A1 20001108 (EN)

Application

EP 99908811 A 19990121

Priority

  • EP 9900384 W 19990121
  • US 1233698 A 19980123
  • US 11072398 P 19981203

Abstract (en)

[origin: WO9937605A1] Compounds of formula (I) and their pharmaceutically acceptable salts are VLA-4 antagonists. They are useful in inhibiting cell adhesion and in the therapeutic or prophylactic treatment of inflammatory and autoimmune diseases, particularly inflammatory airways diseases. They are particularly useful in reducing post-surgical inflammation, especially that resulting from transplant surgery.

IPC 1-7

C07C 275/42; A61K 31/16; A61K 31/17; C07C 237/22

IPC 8 full level

A61K 31/16 (2006.01); A61K 31/167 (2006.01); A61K 31/17 (2006.01); C07C 237/22 (2006.01); C07C 275/42 (2006.01)

CPC (source: EP)

A61K 31/167 (2013.01); A61P 37/06 (2018.01); C07C 237/22 (2013.01); C07C 275/42 (2013.01); C07B 2200/07 (2013.01)

Citation (search report)

See references of WO 9937605A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9937605 A1 19990729; AU 2829299 A 19990809; AU 746174 B2 20020418; BR 9907733 A 20001017; CA 2318639 A1 19990729; CN 1294576 A 20010509; EE 200000428 A 20011217; EP 1049665 A1 20001108; HU 0100336 A2 20010730; HU 0100336 A3 20021128; ID 26665 A 20010125; IL 137329 D0 20010724; JP 2002501039 A 20020115; JP 4564654 B2 20101020; KR 20010034317 A 20010425; NO 20003694 D0 20000719; NO 20003694 L 20000920

DOCDB simple family (application)

EP 9900384 W 19990121; AU 2829299 A 19990121; BR 9907733 A 19990121; CA 2318639 A 19990121; CN 99803780 A 19990121; EE P200000428 A 19990121; EP 99908811 A 19990121; HU 0100336 A 19990121; ID 20001404 A 19990121; IL 13732999 A 19990121; JP 2000528529 A 19990121; KR 20007008039 A 20000722; NO 20003694 A 20000719