EP 1049708 A4 20020904 - METH1 AND METH2 POLYNUCLEOTIDES AND POLYPEPTIDES
Title (en)
METH1 AND METH2 POLYNUCLEOTIDES AND POLYPEPTIDES
Title (de)
METH1- UND METH2- POLYNUKLEOTIDE UND POLYPEPTIDE
Title (fr)
POLYNUCLEOTIDES ET POLYPEPTIDES METH1 ET METH2
Publication
Application
Priority
- US 9901313 W 19990122
- US 7229898 P 19980123
- US 9853998 P 19980828
Abstract (en)
[origin: WO9937660A1] The present invention relates to novel anti-angiogenic proteins, related to thrombospondin. More specifically, isolated nucleic acid molecules are provided encoding human METH1 and METH2. METH1 and METH2 polypeptides are also provided, as are vectors, host cells and recombinant methods for producing the same. Also provided are diagnostic methods for the prognosis of cancer and therapeutic methods for treating individuals in need of an increased amount of METH1 or METH2.
IPC 1-7
C07H 21/04; C07K 14/47; C12N 15/63; C12N 1/21; C12N 15/85; C12N 9/64
IPC 8 full level
C12N 15/09 (2006.01); A61K 38/00 (2006.01); A61K 48/00 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01); C07K 14/47 (2006.01); C07K 14/78 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12P 21/02 (2006.01)
CPC (source: EP KR)
A61P 35/00 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07K 14/515 (2013.01 - KR); C07K 14/78 (2013.01 - EP); C12N 15/113 (2013.01 - KR); C12N 15/63 (2013.01 - KR); A61K 38/00 (2013.01 - EP); A61K 48/00 (2013.01 - EP); C07K 2319/00 (2013.01 - EP); C12N 2799/026 (2013.01 - EP)
Citation (search report)
- [E] EP 1004674 A1 20000531 - KUREHA CHEMICAL IND CO LTD [JP]
- [E] WO 9907850 A1 19990218 - MILLENNIUM BIOTHERAPEUTICS INC [US]
- [DX] DATABASE EMBL [online] EBI; 4 February 1997 (1997-02-04), KUNO K.: "Mouse mRNA for secretory protein containing thrombospondin motifs, complete cds", XP002204902, Database accession no. D67076
- [X] DATABASE EMBL [online] EBI; 31 October 1997 (1997-10-31), NCI-CGAP: "National Cancer Institute, Cancer Genome Anatomy Project (CGAP), Tumor Gene Index", XP002204952, Database accession no. AA635657
- See references of WO 9937660A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9937660 A1 19990729; WO 9937660 A9 19991014; AU 2464199 A 19990809; AU 766787 B2 20031023; CA 2319109 A1 19990729; CN 1292796 A 20010425; EP 1049708 A1 20001108; EP 1049708 A4 20020904; JP 2002501077 A 20020115; KR 20010086224 A 20010910; MX PA00007165 A 20020621; NZ 505855 A 20050128
DOCDB simple family (application)
US 9901313 W 19990122; AU 2464199 A 19990122; CA 2319109 A 19990122; CN 99803495 A 19990122; EP 99904190 A 19990122; JP 2000528581 A 19990122; KR 20007008060 A 20000722; MX PA00007165 A 19990122; NZ 50585599 A 19990122