Global Patent Index - EP 1049710 A1

EP 1049710 A1 2000-11-08 - PEPTIDES WITH BETA-1 INTEGRIN SUBUNIT DEPENDENT CELL ADHESION MODULATING ACTIVITY

Title (en)

PEPTIDES WITH BETA-1 INTEGRIN SUBUNIT DEPENDENT CELL ADHESION MODULATING ACTIVITY

Title (de)

PEPTIDMODULATOREN VON BETA-1-INTEGRIN VERMITTELTER ZELLADHÄSION

Title (fr)

PEPTIDES POSSEDANT UNE ACTIVITE DE MODULATION DE L'ADHERENCE DES CELLULES DEPENDANT DE LA SOUS-UNITE D'INTEGRINE BETA-1

Publication

EP 1049710 A1 (EN)

Application

EP 99902403 A

Priority

  • US 9901236 W
  • US 7211998 P
  • US 9621198 P
  • US 9621298 P

Abstract (en)

[origin: WO9937669A1] Peptides capable of modulating beta 1 integrin subunit dependent cell adhesion which includes a C-terminal aromatic amino acid residue and an amino acid residue having a lipophilic alkyl side chain as the penultimate C-terminal residue are provided. These "LipAr" C-terminated peptides are typically capable of modulating the beta 1 integrin subunit dependent adhesion of cells, such as Ramos cells.

IPC 1-7 (main, further and additional classification)

C07K 7/06; A61K 38/08; C07K 5/10

IPC 8 full level (invention and additional information)

A61K 38/00 (2006.01); A61P 35/04 (2006.01); C07K 5/06 (2006.01); C07K 5/09 (2006.01); C07K 5/10 (2006.01); C07K 5/103 (2006.01); C07K 7/06 (2006.01); C07K 14/78 (2006.01)

CPC (invention and additional information)

C07K 7/06 (2013.01); C07K 5/06034 (2013.01); C07K 5/0817 (2013.01); C07K 5/1008 (2013.01); C07K 14/78 (2013.01); A61K 38/00 (2013.01)

Citation (search report)

See references of WO 9937669A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9937669 A1 19990729; CA 2319207 A1 19990729; EP 1049710 A1 20001108; JP 2002501082 A 20020115

INPADOC legal status


2003-01-02 [18W] WITHDRAWN

- Date of withdrawal: 20021104

2000-11-08 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000802

2000-11-08 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE