Global patent index - EP 1049776 A1

EP 1049776 A1 2000-11-08 - PHAGOCYTOSIS GENES AND USES THEREOF

Title (en)

PHAGOCYTOSIS GENES AND USES THEREOF

Title (de)

PHAGOZYTOSE-GENE UND DEREN ANWENDUNGEN

Title (fr)

GENES DE PHAGOCYTOSE ET LEURS UTILISATIONS

Publication

EP 1049776 A1 (EN)

Application

EP 99902425 A

Priority

  • GB 9812660 A
  • GB 9820816 A
  • US 9901361 W
  • US 7232498 P
  • US 9673198 A
  • US 9634798 A

Abstract (en)

[origin: CA2318935A1] The invention relates to a signal transduction pathway which promotes phagocytosis of apoptotic cells and in particular relates to a protein known as CED-6 in the nematode worm C. elegans, human equivalents of said protein and nucleic acids encoding them. The invention also relates to use of the proteins and encoding nucleic acids in assay methods for detecting compounds which enhance or inhibit the aforesaid signal transduction pathway and use of the proteins, nucleic acids and identified enhancer or inhibitor compounds in methods of treatment of human or animal disease.

IPC 1-7 (main, further and additional classification)

C12N 15/12; A01K 67/027; A61K 38/17; C07K 14/435; C07K 14/47; C07K 16/18; C12N 5/10; C12Q 1/68; G01N 33/53

IPC 8 full level (invention and additional information)

A01K 67/033 (2006.01); A01K 67/027 (2006.01); A61K 31/711 (2006.01); A61K 38/00 (2006.01); A61K 38/17 (2006.01); A61K 48/00 (2006.01); A61P 7/06 (2006.01); A61P 9/10 (2006.01); A61P 25/00 (2006.01); A61P 29/00 (2006.01); A61P 35/00 (2006.01); A61P 37/08 (2006.01); C07K 14/435 (2006.01); C07K 14/47 (2006.01); C07K 16/18 (2006.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); C12N 15/12 (2006.01); C12P 21/08 (2006.01); C12Q 1/68 (2006.01); G01N 33/53 (2006.01); C12R 1/91 (2006.01)

Citation (search report)

See references of WO 9937770A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

AU 2240899 A 19990809; AU 746409 B2 20020502; CA 2318935 A1 19990729; EP 1049776 A1 20001108; JP 2003525569 A 20030902; PL 342082 A1 20010521

INPADOC legal status

2007-08-31 [REG HK WD] APPLICATIONS WITHDRAWN, DEEMED TO BE WITHDRAWN, OR REFUSED AFTER PUBLICATION IN HONG KONG

- Ref Legal Event Code: WD

- Ref Document Number: 1030967

- Country of Ref Document: HK

2004-02-04 [18D] DEEMED TO BE WITHDRAWN

- Ref Legal Event Code: 18D

- Effective date: 20030801

2000-11-08 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 20000724

2000-11-08 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE