Global Patent Index - EP 1049800 A4

EP 1049800 A4 20020925 - ASTHMA RELATED GENES

Title (en)

ASTHMA RELATED GENES

Title (de)

MIT ASTHMA ASSOZIIERTE GENE

Title (fr)

GENES ASSOCIES A L'ASTHME

Publication

EP 1049800 A4 20020925 (EN)

Application

EP 98904649 A 19980121

Priority

US 9801260 W 19980121

Abstract (en)

[origin: WO9937809A1] A genetic locus associated with asthma is identified. The genes within the locus, ASTH1I and ASTH1J, and the regulatory sequences of the locus are characterized. The genes are used to produce the encoded proteins; in screening for compositions that modulate the expression or function of ASTH1 proteins; and in studying associated physiological pathways. The DNA is further used as a diagnostic for genetic predisposition to asthma.

IPC 1-7

C12Q 1/68

IPC 8 full level

A01K 67/027 (2006.01); C07K 14/47 (2006.01); C12N 15/09 (2006.01); C12Q 1/68 (2006.01)

CPC (source: EP)

C07K 14/47 (2013.01)

Citation (search report)

  • [X] WO 9213102 A1 19920806 - GENMARK [US]
  • [X] SLUTSKY A S ET AL: "Genetics of asthma: the University of Toronto Program. University of Toronto Genetics of Asthma Research Group.", AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, (1997 OCT) 15 (4 PT 2) S130-2., XP001088453
  • [Y] ZAMEL N ET AL: "Asthma on Tristan da Cunha: Looking for the genetic link.", AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, vol. 153, no. 6 PART 1, 1996, pages 1902 - 1906, XP001088364, ISSN: 1073-449X
  • [DY] MEYERS D A ET AL: "A genome-wide search for asthma susceptibility loci in ethnically diverse populations.", AMERICAN JOURNAL OF HUMAN GENETICS, vol. 59, no. 4 SUPPL., 1996, 46th Annual Meeting of the American Society of Human Genetics;San Francisco, California, USA; October 29-November 2, 1996, pages A228, XP001088362, ISSN: 0002-9297
  • [DY] DANIELS S ET AL: "A genome-wide search for quantitative trait loci underlying asthma", NATURE, MACMILLAN JOURNALS LTD. LONDON, GB, vol. 383, 19 September 1996 (1996-09-19), pages 247 - 250, XP002110730, ISSN: 0028-0836
  • [X] MAO X -Q ET AL: "Maternal inheritance of atopy at the Fc-epsilon-RI-beta locus in Japanese sibs.", HUMAN HEREDITY, vol. 47, no. 3, 1997, pages 178 - 180, XP001094566, ISSN: 0001-5652
  • [X] DATABASE EMBL [online] "Homo sapiens epithelial-specific transcription factor ESE-1a mRNA, complete cds.", XP002207054, Database accession no. U73844
  • [A] THOMAS N S ET AL: "The candidate region approach to the genetics of asthma and allergy.", AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, vol. 156, no. 4 PART 2, 1997, pages S144 - S151, XP001088365, ISSN: 1073-449X
  • [DA] SPIELMAN RICHARD S ET AL: "Transmission test for linkage disequilibrium: The insulin gene region and insulin-dependent diabetes mellitus (IDDM).", AMERICAN JOURNAL OF HUMAN GENETICS, vol. 52, no. 3, 1993, pages 506 - 516, XP001088448, ISSN: 0002-9297
  • See references of WO 9937809A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9937809 A1 19990729; AU 6247598 A 19990809; CA 2314677 A1 19990729; EP 1049800 A1 20001108; EP 1049800 A4 20020925; JP 2002500895 A 20020115

DOCDB simple family (application)

US 9801260 W 19980121; AU 6247598 A 19980121; CA 2314677 A 19980121; EP 98904649 A 19980121; JP 2000528715 A 19980121