EP 1050061 A2 20001108 - SPECTROMETER PROVIDED WITH PULSED ION SOURCE AND TRANSMISSION DEVICE TO DAMP ION MOTION AND METHOD OF USE
Title (en)
SPECTROMETER PROVIDED WITH PULSED ION SOURCE AND TRANSMISSION DEVICE TO DAMP ION MOTION AND METHOD OF USE
Title (de)
SPEKTROMETER MIT GEPULSTER IONENQUELLE, KOPPLUNGSVORRICHTUNG ZUR DÄMPFUNG DER IONENBEWEGUNG, UND METHODE ZUR VERWENDUNG DERSELBEN
Title (fr)
SPECTROMETRE A SOURCE IONIQUE A IMPULSIONS ET APPAREIL DE TRANSMISSION VISANT A AMORTIR LA MOBILITE IONIQUE, ET PROCEDE D'UTILISATION
Publication
Application
Priority
- CA 9900034 W 19990125
- CA 2227806 A 19980123
Abstract (en)
[origin: WO9938185A2] A method and apparatus are provided for providing an ion transmission device or interface between an ion source and a spectrometer. The ion transmission device can include a multipole rod set and includes a damping gas, to damp spatial and energy spreads of ions generated by a pulsed ion source. The multipole rod set has the effect of guiding the ions along an ion path, so that they can be directed into the inlet of a mass spectrometer. The invention has particular application to MALDI (matrix-assisted laser desorption/ionization) ion sources, which produce a small supersonic jet of matrix molecules and ions, which is substantially non-directional, and can have ions travelling in all available directions from the source and having a wide range of energy spreads. The ion transmission device can have a number of effects, including: substantially spreading out the generated ions along an ion axis to generate a quasi-continuous beam; reducing the energy spread of ions emitted from the source; and at least partially suppressing unwanted fragmentation of analyte ions. Consequently, a number of pulses of ions can be delivered to the time-of-flight or other spectrometer, for each cycle of the ion generation.
IPC 1-7
IPC 8 full level
H01J 49/42 (2006.01); H01J 1/00 (2006.01); H01J 49/10 (2006.01); H01J 49/40 (2006.01)
CPC (source: EP)
H01J 49/063 (2013.01); H01J 49/164 (2013.01); H01J 49/40 (2013.01)
Citation (search report)
See references of WO 9938185A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9938185 A2 19990729; WO 9938185 A3 19991021; AT E273561 T2 20040815; AU 2042899 A 19990809; AU 745866 B2 20020411; CA 2227806 A1 19990723; CA 2227806 C 20060718; DE 1050061 T1 20010607; DE 69919325 D1 20040916; DE 69919325 T2 20050217; DE 69919325 T3 20170302; DK 1050061 T3 20041122; DK 1050061 T4 20170123; EP 1050061 A2 20001108; EP 1050061 B1 20040811; EP 1050061 B2 20161019; JP 2002502084 A 20020122; JP 4331398 B2 20090916
DOCDB simple family (application)
CA 9900034 W 19990125; AT 99900849 T 19990125; AU 2042899 A 19990125; CA 2227806 A 19980123; DE 69919325 T 19990125; DE 99900849 T 19990125; DK 99900849 T 19990125; EP 99900849 A 19990125; JP 2000528992 A 19990125