Global Patent Index - EP 1051391 A1

EP 1051391 A1 2000-11-15 - N-ALKYLATION OF 5-AMINO-2,4,6-TRIIODO-ISOPHTHALAMIDES

Title (en)

N-ALKYLATION OF 5-AMINO-2,4,6-TRIIODO-ISOPHTHALAMIDES

Title (de)

N-ALKYLIERUNG VON 5-AMINO-2,4,6-TRIIOD-ISOPHTALAMIDEN

Title (fr)

N-ALKYLATION DE 5-AMINO-2,4,6-TRIODO-ISOPHTALAMIDES

Publication

EP 1051391 A1 (EN)

Application

EP 98955788 A

Priority

  • GB 9803535 W
  • GB 9725010 A

Abstract (en)

[origin: WO9926916A1] The present invention provides a process for the preparation of a non-ionic 5-(N-2, 3-dihydroxypropyl -acylamino)-2,4, 6-triiodo-N,N'-disubstituted -isophthalamide which process comprises reacting a non-ionic 5-acylamino-2, 4,6-triiodo-N, N'-disubstituted -isophthalamide with an oxirane in a solvent and in the presence of up to 7 mole percent of a strong base.

IPC 1-7 (main, further and additional classification)

C07C 231/12; A61K 31/165; A61K 49/04; C07C 233/05; C07C 233/65

IPC 8 full level (invention and additional information)

C07C 231/12 (2006.01); C07C 237/46 (2006.01)

CPC (invention and additional information)

C07C 231/12 (2013.01)

Combination set (CPC)

C07C 231/12 + C07C 237/46

Citation (search report)

See references of WO 9926916A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9926916 A1 19990603; AU 1251399 A 19990615; EP 1051391 A1 20001115; GB 9725010 D0 19980128

INPADOC legal status


2002-12-11 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20020601

2000-11-15 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000420

2000-11-15 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE