EP 1051429 A1 20001115 - LDL RELATED PROTEIN AND USES THEREOF
Title (en)
LDL RELATED PROTEIN AND USES THEREOF
Title (de)
LDL-VERWANDTES PROTEIN UND SEINE VERWENDUNG
Title (fr)
PROTEINE APPARENTEE AUX LDL ET SON UTILISATION
Publication
Application
Priority
- US 9925178 W 19991027
- US 18317598 A 19981030
Abstract (en)
[origin: WO0026227A1] The invention provides isolated nucleic acid molecules, designated TANGO 136 nucleic acid molecules, which encode transmembrane proteins with homology to members of the LDL receptor family of proteins. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing the nucleic acid molecules of the invention, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which a nucleic acid molecule of the invention has been introduced or disrupted. The invention still further provides isolated polypeptides, fusion polypeptides, antigenic peptides and antibodies. Diagnostic, screening, and therapeutic methods utilizing compositions of the invention are also provided.
IPC 1-7
C07H 21/04; C12N 1/21; C12N 15/00; C12N 15/63; C07K 14/705; G01N 33/53; C12Q 1/68
IPC 8 full level
A61K 31/7088 (2006.01); A61K 38/00 (2006.01); A61K 48/00 (2006.01); A61P 3/10 (2006.01); A61P 5/16 (2006.01); A61P 7/02 (2006.01); A61P 9/10 (2006.01); A61P 13/12 (2006.01); A61P 25/14 (2006.01); A61P 25/16 (2006.01); A61P 25/18 (2006.01); A61P 25/24 (2006.01); A61P 25/28 (2006.01); C07K 14/47 (2006.01); C07K 14/705 (2006.01); C07K 16/18 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); C12Q 1/68 (2006.01); G01N 33/15 (2006.01); G01N 33/50 (2006.01); G01N 33/53 (2006.01); G01N 33/566 (2006.01)
CPC (source: EP)
A61P 3/10 (2017.12); A61P 5/16 (2017.12); A61P 7/02 (2017.12); A61P 9/10 (2017.12); A61P 13/12 (2017.12); A61P 25/14 (2017.12); A61P 25/16 (2017.12); A61P 25/18 (2017.12); A61P 25/24 (2017.12); A61P 25/28 (2017.12); C07K 14/705 (2013.01)
Citation (search report)
See references of WO 0026227A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0026227 A1 20000511; WO 0026227 A9 20000921; AU 1236600 A 20000522; CA 2317117 A1 20000511; EP 1051429 A1 20001115; JP 2002529053 A 20020910
DOCDB simple family (application)
US 9925178 W 19991027; AU 1236600 A 19991027; CA 2317117 A 19991027; EP 99971425 A 19991027; JP 2000579615 A 19991027