EP 1053003 A1 20001122 - COMPOSITIONS AND METHODS FOR SEPARATING LENS EPITHELIAL CELLS AND PREVENTING POSTERIOR CAPSULAR OPACIFICATION
Title (en)
COMPOSITIONS AND METHODS FOR SEPARATING LENS EPITHELIAL CELLS AND PREVENTING POSTERIOR CAPSULAR OPACIFICATION
Title (de)
ZUSAMMENSETZUNGEN UND METHODEN ZUR TRENNUNG VON LINSENEPITHELZELLEN UND ZUR VERHINDERUNG VON SPÄTERER TRÜBUNG DER LINSENKAPSEL
Title (fr)
COMPOSITIONS ET PROCEDES POUR SEPARER LES CELLULES EPITHELIALES DU CRISTALLIN ET EMPECHER L'OPACIFICATION CAPSULAIRE POSTERIEURE
Publication
Application
Priority
- IB 9900905 W 19990202
- US 1771698 A 19980204
Abstract (en)
[origin: WO9939722A2] Posterior capsular opacification can be prevented by modulating focal contacts, which mediate adhesion between lens epithelial cells and the lens capsule, using a treating solution containing a focal contact-modulating substance or a proenzyme, such as Lys-plasminogen, which is introduced into the lens capsular bag during cataract surgery. To secure the passage of a treating solution between the lens epithelial cells, a calcium chelating agent, such as ethylenediamine tetraacetic acid (EDTA), is included in a treating solution. To limit the effect of the treating solution to lens epithelial cells prior to, during, and/or after capsulotomy, and inhibitor, such as omega -amino acid, can be introduced into the anterior chamber before the treating solution as a mixture with a viscoelastic material, such as sodium hyaluronate, or into the lens capsular bag without a viscoelastic material during capsulotomy.
IPC 1-7
IPC 8 full level
A61K 38/43 (2006.01); A61K 38/48 (2006.01); A61K 45/00 (2006.01); A61P 27/02 (2006.01); A61P 27/12 (2006.01)
CPC (source: EP)
A61K 38/484 (2013.01); A61P 27/02 (2017.12); A61P 27/12 (2017.12)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9939722 A2 19990812; WO 9939722 A3 19991223; AU 3624299 A 19990823; EP 1053003 A1 20001122; JP 2002502821 A 20020129
DOCDB simple family (application)
IB 9900905 W 19990202; AU 3624299 A 19990202; EP 99918229 A 19990202; JP 2000530219 A 19990202