Global Patent Index - EP 1053003 A1

EP 1053003 A1 2000-11-22 - COMPOSITIONS AND METHODS FOR SEPARATING LENS EPITHELIAL CELLS AND PREVENTING POSTERIOR CAPSULAR OPACIFICATION

Title (en)

COMPOSITIONS AND METHODS FOR SEPARATING LENS EPITHELIAL CELLS AND PREVENTING POSTERIOR CAPSULAR OPACIFICATION

Title (de)

ZUSAMMENSETZUNGEN UND METHODEN ZUR TRENNUNG VON LINSENEPITHELZELLEN UND ZUR VERHINDERUNG VON SPÄTERER TRÜBUNG DER LINSENKAPSEL

Title (fr)

COMPOSITIONS ET PROCEDES POUR SEPARER LES CELLULES EPITHELIALES DU CRISTALLIN ET EMPECHER L'OPACIFICATION CAPSULAIRE POSTERIEURE

Publication

EP 1053003 A1 (EN)

Application

EP 99918229 A

Priority

  • IB 9900905 W
  • US 1771698 A

Abstract (en)

[origin: WO9939722A2] Posterior capsular opacification can be prevented by modulating focal contacts, which mediate adhesion between lens epithelial cells and the lens capsule, using a treating solution containing a focal contact-modulating substance or a proenzyme, such as Lys-plasminogen, which is introduced into the lens capsular bag during cataract surgery. To secure the passage of a treating solution between the lens epithelial cells, a calcium chelating agent, such as ethylenediamine tetraacetic acid (EDTA), is included in a treating solution. To limit the effect of the treating solution to lens epithelial cells prior to, during, and/or after capsulotomy, and inhibitor, such as omega -amino acid, can be introduced into the anterior chamber before the treating solution as a mixture with a viscoelastic material, such as sodium hyaluronate, or into the lens capsular bag without a viscoelastic material during capsulotomy.

IPC 1-7 (main, further and additional classification)

A61K 38/00

IPC 8 full level (invention and additional information)

A61K 45/00 (2006.01); A61K 38/43 (2006.01); A61K 38/48 (2006.01); A61P 27/02 (2006.01); A61P 27/12 (2006.01)

CPC (invention and additional information)

A61K 38/484 (2013.01)

Combination set (CPC)

A61K 38/484 + A61K 2300/00

Citation (search report)

See references of WO 9939722A3

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9939722 A2 19990812; WO 9939722 A3 19991223; AU 3624299 A 19990823; EP 1053003 A1 20001122; JP 2002502821 A 20020129

INPADOC legal status


2001-12-19 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20010616

2001-01-17 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20001205

2000-11-22 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000829

2000-11-22 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE