EP 1053335 A1 20001122 - STREPTOMYCES AVERMITILIS GENE DIRECTING THE RATIO OF B2:B1 AVERMECTINS
Title (en)
STREPTOMYCES AVERMITILIS GENE DIRECTING THE RATIO OF B2:B1 AVERMECTINS
Title (de)
STREPTOMYCES AVERMILITIS GEN ZUM REGULIEREN DES VERHÄLTNISSES DER B2:B1 AVERMECTINEN
Title (fr)
GENE DE STREPTOMYCES AVERMITILIS COMMANDANT LE RAPPORT D'AVERMECTINES B2/B1
Publication
Application
Priority
- IB 9900130 W 19990125
- US 7463698 P 19980213
Abstract (en)
[origin: WO9941389A1] The present invention relates to polynucleotide molecules comprising nucleotide sequences encoding an aveC gene product, which polynucleotide molecules can be used to alter the ratio or amount of class 2:1 avermectins produced in fermentation cultures of S. avermitilis. The present invention further relates to vectors, host cells, and mutant strains of S. avermitilis in which the aveC gene has been inactivated, or mutated so as to change the ratio or amount of class 2:1 avermectins produced.
IPC 1-7
C12N 15/60; C12N 15/52; C12N 9/88; C12N 15/76; C12P 19/62; C12P 17/18; C12Q 1/527; C12N 1/21
IPC 8 full level
C07H 21/00 (2006.01); C07K 14/36 (2006.01); C12N 1/21 (2006.01); C12N 9/88 (2006.01); C12N 15/09 (2006.01); C12N 15/31 (2006.01); C12N 15/52 (2006.01); C12N 15/76 (2006.01); C12P 17/18 (2006.01); C12P 19/62 (2006.01); C12N 15/11 (2006.01); C12Q 1/527 (2006.01); C12N 15/60 (2006.01); C12Q 1/68 (2006.01); C12R 1/465 (2006.01)
CPC (source: EP KR)
C12N 9/88 (2013.01 - EP); C12N 15/11 (2013.01 - KR); C12N 15/76 (2013.01 - EP); C12P 17/181 (2013.01 - EP); C12P 19/62 (2013.01 - EP)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE
Designated extension state (EPC)
AL LT LV MK RO SI
DOCDB simple family (publication)
WO 9941389 A1 19990819; AP 9901463 A0 19990331; AR 018085 A1 20011031; AU 1887899 A 19990830; AU 752343 B2 20020919; AU 752343 C 20051103; BG 104759 A 20010430; BG 64911 B1 20060831; BR 9907893 A 20001114; CA 2320031 A1 19990819; CA 2521289 A1 19990819; CN 1297485 A 20010530; CN 1521180 A 20040818; CO 5070698 A1 20010828; DZ 2720 A1 20030901; EA 003905 B1 20031030; EA 200000758 A1 20010423; EP 1053335 A1 20001122; GT 199900014 A 20000725; HN 1999000008 A 19991029; HR P20000539 A2 20010430; HU P0100784 A2 20010628; HU P0100784 A3 20041028; IL 137610 A0 20010724; IL 183596 A0 20070920; IS 5567 A 20000720; JP 2002503473 A 20020205; JP 2004283174 A 20041014; JP 4011036 B2 20071121; KR 100499214 B1 20050707; KR 20010052166 A 20010625; KR 20040053390 A 20040623; KR 20040099389 A 20041126; MA 24760 A1 19991001; NO 20004044 D0 20000811; NO 20004044 L 20001011; NZ 505676 A 20030228; NZ 518657 A 20031031; OA 11449 A 20031203; PA 8467601 A1 20000929; PE 20000352 A1 20000516; PL 194270 B1 20070531; PL 342468 A1 20010604; SK 11722000 A3 20010409; TN SN99017 A1 20051110; TW 585910 B 20040501; YU 50900 A 20040312; ZA 991138 B 20000814
DOCDB simple family (application)
IB 9900130 W 19990125; AP 9901463 A 19990211; AR P990100571 A 19990211; AU 1887899 A 19990125; BG 10475900 A 20000912; BR 9907893 A 19990125; CA 2320031 A 19990125; CA 2521289 A 19990125; CN 200410005415 A 19990125; CN 99805027 A 19990125; CO 99008652 A 19990212; DZ 990021 A 19990210; EA 200000758 A 19990125; EP 99900270 A 19990125; GT 199900014 A 19990201; HN 1999000008 A 19990205; HR P20000539 A 20000811; HU P0100784 A 19990125; IL 13761099 A 19990125; IL 18359607 A 20070531; IS 5567 A 20000720; JP 2000531570 A 19990125; JP 2004130624 A 20040427; KR 20007008870 A 20000812; KR 20047008310 A 19990125; KR 20047015691 A 19990125; MA 25460 A 19990210; NO 20004044 A 20000811; NZ 50567699 A 19990125; NZ 51865799 A 19990125; OA 1200000217 A 20000804; PA 8467601 A 19990126; PE 00009999 A 19990208; PL 34246899 A 19990125; SK 11722000 A 19990125; TN SN99017 A 19990210; TW 88102005 A 19990209; YU 50900 A 19990125; ZA 991138 A 19990212