EP 1054673 A1 20001129 - BENZOXAZINE COMPOUNDS FOR ENHANCING SYNAPTIC RESPONSE
Title (en)
BENZOXAZINE COMPOUNDS FOR ENHANCING SYNAPTIC RESPONSE
Title (de)
BENZOXAZIN-DERIVATE ZUR ERHÖHUNG DER SYNAPTISCHEN REAKTION
Title (fr)
UTILISATION DE COMPOSES BENZOXAZINIQUES POUR STIMULER LA REPONSE SYNAPTIQUE
Publication
Application
Priority
- US 9827027 W 19981216
- US 99830097 A 19971224
Abstract (en)
[origin: WO9933469A1] Compounds having a certain benzoxazine ring system and their precursors are disclosed which are useful for enhancing synaptic responses mediated by AMPA receptors. Also disclosed are methods for preparing such compounds, and methods for their use in treating subjects suffering from impaired nervous or intellectual functioning due to deficiencies in the number of excitatory synapses or in the number of AMPA receptors. The invention compounds can also be used for the treatment of non-impaired subjects for enhancing performance in sensory-motor and cognitive tasks which depend on brain networks utilizing AMPA receptors and for improving memory encoding.
IPC 1-7
IPC 8 full level
A61K 31/5365 (2006.01); A61K 31/542 (2006.01); A61P 25/00 (2006.01); A61P 25/18 (2006.01); A61P 25/24 (2006.01); A61P 25/28 (2006.01); A61P 43/00 (2006.01); C07D 498/14 (2006.01); C07D 513/14 (2006.01)
CPC (source: EP KR US)
A61K 31/535 (2013.01 - KR); A61P 25/00 (2018.01 - EP); A61P 25/18 (2018.01 - EP); A61P 25/24 (2018.01 - EP); A61P 25/28 (2018.01 - EP); A61P 43/00 (2018.01 - EP); C07D 513/14 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9933469 A1 19990708; AT E261306 T1 20040315; AU 1930599 A 19990719; AU 746971 B2 20020509; BR 9814478 A 20001010; CA 2316356 A1 19990708; CA 2316356 C 20091103; CN 1160360 C 20040804; CN 1283114 A 20010207; DE 69822344 D1 20040415; DE 69822344 T2 20050217; DK 1054673 T3 20040705; EP 1054673 A1 20001129; EP 1054673 A4 20010718; EP 1054673 B1 20040310; ES 2217615 T3 20041101; HU P0102056 A2 20011128; HU P0102056 A3 20030328; IL 136783 A0 20010614; IL 136783 A 20051120; JP 2001527045 A 20011225; JP 4620244 B2 20110126; KR 100561049 B1 20060316; KR 20010033615 A 20010425; MX PA00006155 A 20020424; NO 20003166 D0 20000619; NO 20003166 L 20000807; NO 325764 B1 20080714; NZ 505212 A 20030228; PL 194905 B1 20070731; PL 341427 A1 20010409; PT 1054673 E 20040831; RU 2246497 C2 20050220; TR 200001971 T2 20010122; US 5985871 A 19991116
DOCDB simple family (application)
US 9827027 W 19981216; AT 98964112 T 19981216; AU 1930599 A 19981216; BR 9814478 A 19981216; CA 2316356 A 19981216; CN 98812539 A 19981216; DE 69822344 T 19981216; DK 98964112 T 19981216; EP 98964112 A 19981216; ES 98964112 T 19981216; HU P0102056 A 19981216; IL 13678398 A 19981216; JP 2000526226 A 19981216; KR 20007007128 A 20000624; MX PA00006155 A 19981216; NO 20003166 A 20000619; NZ 50521200 A 20000616; PL 34142798 A 19981216; PT 98964112 T 19981216; RU 2000119735 A 19981216; TR 200001971 T 19981216; US 99830097 A 19971224