Global Patent Index - EP 1054989 A1

EP 1054989 A1 20001129 - METHODS FOR PSEUDOADENOVIRAL VECTOR PRODUCTION

Title (en)

METHODS FOR PSEUDOADENOVIRAL VECTOR PRODUCTION

Title (de)

METHODEN FÜR DIE PRODUKTION VON PSEUDOADENOVIRALEN VEKTOREN

Title (fr)

PROCEDES DE FABRICATION DE VECTEURS PSEUDO-ADENOVIRAUX

Publication

EP 1054989 A1 20001129 (EN)

Application

EP 99908233 A 19990217

Priority

  • US 9903483 W 19990217
  • US 7476198 P 19980217
  • US 8652898 P 19980522

Abstract (en)

[origin: WO9941400A1] The invention is directed to helper adenoviruses which facilitate the production of pseudoadenoviral vectors (PAV) but which cannot be packaged into viral particles. The invention is further directed to novel PAV producer cell lines expressing DNA binding and/or repressor proteins that prevent the packaging of the helper viruses. The invention is also directed to methods for the production of PAV in such cell lines with minimal contamination from helper viruses.

IPC 1-7

C12N 15/86; C12N 5/10

IPC 8 full level

C12N 15/09 (2006.01); C12N 5/10 (2006.01); C12N 7/00 (2006.01); C12N 15/861 (2006.01)

CPC (source: EP)

C12N 15/86 (2013.01); C12N 2710/10343 (2013.01); C12N 2800/108 (2013.01); C12N 2800/30 (2013.01); C12N 2830/003 (2013.01); C12N 2830/42 (2013.01)

Citation (search report)

See references of WO 9941400A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9941400 A1 19990819; AU 2771899 A 19990830; AU 752284 B2 20020912; CA 2318737 A1 19990819; EP 1054989 A1 20001129; JP 2002538758 A 20021119

DOCDB simple family (application)

US 9903483 W 19990217; AU 2771899 A 19990217; CA 2318737 A 19990217; EP 99908233 A 19990217; JP 2000531581 A 19990217