Global Patent Index - EP 1054997 A1

EP 1054997 A1 2000-11-29 - METHOD FOR DEVELOPING A PHARMACEUTICAL ACTIVE INGREDIENT

Title (en)

METHOD FOR DEVELOPING A PHARMACEUTICAL ACTIVE INGREDIENT

Title (de)

VERFAHREN ZUR ENTWICKLUNG EINES PHARMAZEUTISCHEN WIRKSTOFFES

Title (fr)

PROCEDE DE DEVELOPPEMENT D'UN PRINCIPE ACTIF PHARMACEUTIQUE

Publication

EP 1054997 A1 (DE)

Application

EP 99911661 A

Priority

  • DE 19805334 A
  • EP 9900876 W

Abstract (en)

[origin: DE19805334A1] The invention relates to a method for developing an active ingredient capable of directly or indirectly influencing, preferably in an intracellular manner, the function of physiologically active peptides or proteins. The influence on the function of the peptides or proteins preferably takes the form of an inhibition of said function. According to the method, first a target peptide or target protein which is able to or does physiologically participate in a peptide-peptide or protein-protein interaction is identified and selected. Usually only the identification or selection or one or more fragments of said peptide or protein is necessary. Secondly an amino acid sequence is derived or screened which interacts with the target peptide or target protein or with fragments thereof with high affinity. The derived amino acid sequence interacts with the target peptide preferably at least as well as and especially better than with its physiological interaction partner.

IPC 1-7 (main, further and additional classification)

C12Q 1/02; C12N 15/10; C12Q 1/68; G01N 33/50; G01N 33/68

IPC 8 full level (invention and additional information)

G01N 33/566 (2006.01); A61K 38/00 (2006.01); A61K 48/00 (2006.01); C12N 15/09 (2006.01); C12N 15/10 (2006.01); C12Q 1/02 (2006.01); C12Q 1/68 (2006.01); C40B 30/04 (2006.01); G01N 33/542 (2006.01); G01N 33/68 (2006.01)

CPC (invention and additional information)

C12N 15/1055 (2013.01); C12Q 1/025 (2013.01); C40B 30/04 (2013.01); G01N 33/542 (2013.01); G01N 33/6803 (2013.01); G01N 33/6845 (2013.01)

Citation (search report)

See references of WO 9941407A1

Designated contracting state (EPC)

AT CH DE ES FR GB IT LI

EPO simple patent family

DE 19805334 A1 19990812; AU 3027499 A 19990830; EP 1054997 A1 20001129; JP 2002503481 A 20020205; WO 9941407 A1 19990819

INPADOC legal status


2004-03-17 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20030902

2000-11-29 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000901

2000-11-29 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT CH DE ES FR GB IT LI