EP 1056335 A1 20001206 - METHOD OF PROCESSING AND PRESERVING COLLAGEN BASED TISSUES
Title (en)
METHOD OF PROCESSING AND PRESERVING COLLAGEN BASED TISSUES
Title (de)
VERFAHREN ZUR BEHANDLUNG UND KONSERVIERUNG VON AUF KOLLAGEN BASIERTEN GEWEBETEILEN
Title (fr)
PROCEDE PERMETTANT DE TRAITER ET DE CONSERVER DES TISSUS A BASE DE COLLAGENE
Publication
Application
Priority
- US 9903667 W 19990219
- US 7547298 P 19980220
Abstract (en)
[origin: WO9941981A1] A process for the preserving collagen-based tissues involves procuring the collagen-based tissue; treating the tissue in a detergent solution; treating the tissue in an enzyme solution; treating the tissue so as to prevent or inhibit the molecular crosslinking of processed tissues via the Maillard reaction and the subsequent formation of advanced glycosylation end products; treating the tissue so as to prevent or inhibit the molecular crosslinking of processed tissues via reactive oxidative species of molecules; treating the tissue so as to prevent or inhibit the molecular crosslinking of processed tissues via the formation and propagation of molecular free radicals; treating the tissue in a cryopreservation solution; and cryopreserving the tissue. The process may be utlized to preserve several differing types of collagen based tissue including heart valve, vascular grafts including veins and arteries, umbilical vessels, nerve and nervous system tissue, dura, dermis and other similar collagen based tissues.
IPC 1-7
IPC 8 full level
A01N 1/00 (2006.01); A01N 1/02 (2006.01); A61L 27/00 (2006.01)
CPC (source: EP)
A01N 1/02 (2013.01); A01N 1/0221 (2013.01); A61L 27/3687 (2013.01)
Citation (search report)
See references of WO 9941981A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9941981 A1 19990826; AU 2775399 A 19990906; AU 752457 B2 20020919; CA 2320887 A1 19990826; EP 1056335 A1 20001206; JP 2002503678 A 20020205
DOCDB simple family (application)
US 9903667 W 19990219; AU 2775399 A 19990219; CA 2320887 A 19990219; EP 99908285 A 19990219; JP 2000532008 A 19990219