EP 1056471 A1 20001206 - TREATING ATOPIC DERMATITIS WITH IgE ANTAGONISTS
Title (en)
TREATING ATOPIC DERMATITIS WITH IgE ANTAGONISTS
Title (de)
BEHANDLUNG ATOPISCHER DERMATITIS MIT IgE ANTAGONISTEN
Title (fr)
TRAITEMENT DE LA DERMATITE ATOPIQUE A L'AIDE D'ANTAGONISTES D'IgE
Publication
Application
Priority
- US 9900135 W 19990106
- US 1526998 A 19980129
- US 7303398 P 19980129
Abstract (en)
[origin: WO9938531A1] The invention relates to a pharmaceutical composition for treatment of atopic dermatitis comprising a suitable IgE antagonist which does not induce release of the mediators of allergy; for example, anti-IgE antibodies which bind to secreted IgE, to membrane IgE on the surface of IgE-producing B cells, but not to IgE bound to the Fc epsilon RI on the surface of basophils or mast cells. Preferably, these antibodies also do not bind to IgE bound to Fc epsilon RII receptors. It is also preferable if these antibodies have human IgG1 or IgG3 constant regions, as well as further human portions, if desired. The pharmaceutical composition can be administered systemically or topically.
IPC 1-7
IPC 8 full level
A61K 39/395 (2006.01); A61K 45/00 (2006.01); A61P 17/00 (2006.01); A61P 37/08 (2006.01); C07K 16/42 (2006.01); C12N 15/02 (2006.01); A61K 38/00 (2006.01)
CPC (source: EP)
A61P 17/00 (2017.12); A61P 37/08 (2017.12); C07K 16/4291 (2013.01); A61K 38/00 (2013.01); C07K 2317/24 (2013.01)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9938531 A1 19990805; AU 2103699 A 19990816; CN 1289253 A 20010328; EP 1056471 A1 20001206; EP 1056471 A4 20010530; JP 2002501905 A 20020122
DOCDB simple family (application)
US 9900135 W 19990106; AU 2103699 A 19990106; CN 99802505 A 19990106; EP 99901309 A 19990106; JP 2000529263 A 19990106