EP 1056886 A1 20001206 - HLA LINKED PRE-ECLAMPSIA AND MISCARRIAGE SUSCEPTIBILITY GENE
Title (en)
HLA LINKED PRE-ECLAMPSIA AND MISCARRIAGE SUSCEPTIBILITY GENE
Title (de)
HLA-VERBUNDENE PRE-ECLAMPSIA UND FEHLGEBURT EMPFINDLICHKEITSGEN
Title (fr)
GENE DE SUSCEPTIBILITE A LA PRE-ECLAMPSIE ET AUX FAUSSES-COUCHES LIE AU HLA
Publication
Application
Priority
- IE 9900012 W 19990225
- IE 980134 A 19980225
- IE 980668 A 19980812
Abstract (en)
[origin: WO9943851A1] The invention relates to the identification of a susceptibility gene for pre-eclampsia and eclampsia and provides methods and diagnostic kits for diagnosing susceptibility to normal pregnancy, pre-eclampsia, eclampsia, intrauterine growth retardation, miscarriage or miscarriage-related infertility. The invention is based on analysing HLA-G or HLA-G linked nucleic acid, or HLA-G protein or HLA-G mRNA or cells or molecules whose concentration changes as a result of HLA-G action. The invention also provides pharmaceutical compositions for and methods of treatment of the above conditions.
IPC 1-7
C12Q 1/68; C12Q 1/02; C12N 15/12; G01N 33/50; G01N 33/564; A61K 38/17; A61K 35/14; A61K 39/395
IPC 8 full level
A61K 35/14 (2006.01); A61K 38/00 (2006.01); A61K 39/395 (2006.01); A61K 45/00 (2006.01); A61P 15/00 (2006.01); A61P 15/06 (2006.01); A61P 15/08 (2006.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); C12N 15/12 (2006.01); C12Q 1/02 (2006.01); C12Q 1/68 (2006.01); G01N 33/15 (2006.01); G01N 33/50 (2006.01); G01N 33/564 (2006.01); G01N 33/569 (2006.01); G01N 33/68 (2006.01)
CPC (source: EP)
A61P 15/00 (2017.12); A61P 15/06 (2017.12); A61P 15/08 (2017.12); C12Q 1/6881 (2013.01); G01N 33/5008 (2013.01); G01N 33/502 (2013.01); G01N 33/5044 (2013.01); G01N 33/5091 (2013.01); G01N 33/56977 (2013.01); C12Q 2600/156 (2013.01); C12Q 2600/158 (2013.01); C12Q 2600/172 (2013.01); G01N 2500/00 (2013.01)
Citation (search report)
See references of WO 9943851A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9943851 A1 19990902; AU 2003231618 A1 20030911; AU 2636399 A 19990915; CA 2321223 A1 19990902; EP 1056886 A1 20001206; JP 2003517267 A 20030527; NO 20004222 D0 20000823; NO 20004222 L 20001024
DOCDB simple family (application)
IE 9900012 W 19990225; AU 2003231618 A 20030805; AU 2636399 A 19990225; CA 2321223 A 19990225; EP 99906418 A 19990225; JP 2000533590 A 19990225; NO 20004222 A 20000823