Global Patent Index - EP 1056886 A1

EP 1056886 A1 2000-12-06 - HLA LINKED PRE-ECLAMPSIA AND MISCARRIAGE SUSCEPTIBILITY GENE

Title (en)

HLA LINKED PRE-ECLAMPSIA AND MISCARRIAGE SUSCEPTIBILITY GENE

Title (de)

HLA-VERBUNDENE PRE-ECLAMPSIA UND FEHLGEBURT EMPFINDLICHKEITSGEN

Title (fr)

GENE DE SUSCEPTIBILITE A LA PRE-ECLAMPSIE ET AUX FAUSSES-COUCHES LIE AU HLA

Publication

EP 1056886 A1 (EN)

Application

EP 99906418 A

Priority

  • IE 9900012 W
  • IE 980134 A
  • IE 980668 A

Abstract (en)

[origin: WO9943851A1] The invention relates to the identification of a susceptibility gene for pre-eclampsia and eclampsia and provides methods and diagnostic kits for diagnosing susceptibility to normal pregnancy, pre-eclampsia, eclampsia, intrauterine growth retardation, miscarriage or miscarriage-related infertility. The invention is based on analysing HLA-G or HLA-G linked nucleic acid, or HLA-G protein or HLA-G mRNA or cells or molecules whose concentration changes as a result of HLA-G action. The invention also provides pharmaceutical compositions for and methods of treatment of the above conditions.

IPC 1-7 (main, further and additional classification)

C12Q 1/68; A61K 35/14; A61K 38/17; A61K 39/395; C12N 15/12; C12Q 1/02; G01N 33/50; G01N 33/564

IPC 8 full level (invention and additional information)

A61K 35/14 (2006.01); A61K 38/00 (2006.01); A61K 39/395 (2006.01); A61K 45/00 (2006.01); A61P 15/00 (2006.01); A61P 15/06 (2006.01); A61P 15/08 (2006.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); C12N 15/12 (2006.01); C12Q 1/02 (2006.01); C12Q 1/68 (2006.01); G01N 33/15 (2006.01); G01N 33/50 (2006.01); G01N 33/564 (2006.01); G01N 33/569 (2006.01); G01N 33/68 (2006.01)

CPC (invention and additional information)

G01N 33/5091 (2013.01); C12Q 1/6881 (2013.01); G01N 33/5008 (2013.01); G01N 33/502 (2013.01); G01N 33/5044 (2013.01); G01N 33/56977 (2013.01); C12Q 2600/156 (2013.01); C12Q 2600/158 (2013.01); C12Q 2600/172 (2013.01); G01N 2500/00 (2013.01)

Citation (search report)

See references of WO 9943851A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9943851 A1 19990902; AU 2003231618 A1 20030911; AU 2636399 A 19990915; CA 2321223 A1 19990902; EP 1056886 A1 20001206; JP 2003517267 A 20030527; NO 20004222 A 20001024; NO 20004222 D0 20000823

INPADOC legal status


2005-03-09 [18D] DEEMED TO BE WITHDRAWN

- Ref Legal Event Code: 18D

- Effective date: 20040831

2000-12-06 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 20000816

2000-12-06 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2000-12-06 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Ref Legal Event Code: AX

- Free Format Text: AL PAYMENT 20000816;LT PAYMENT 20000816;LV PAYMENT 20000816;MK PAYMENT 20000816;RO PAYMENT 20000816;SI PAYMENT 20000816