EP 1057209 A4 20060201 - MASS SPECTROMETRY WITH MULTIPOLE ION GUIDE
Title (en)
MASS SPECTROMETRY WITH MULTIPOLE ION GUIDE
Title (de)
MASSEN SPEKTROMETRIE MIT MULTIPOLARER IONEN FÜHRUNGMITTEL
Title (fr)
SPECTROMETRIE DE MASSE A GUIDE D'IONS MULTIPOLAIRE
Publication
Application
Priority
- US 9901335 W 19990122
- US 7237498 P 19980123
- US 8724698 P 19980529
Abstract (en)
[origin: WO9938193A1] Multipole ion guides (6) configured with one or more segments (1, 2, 3, 4) and positioned in a higher pressure vacuum region (72), are operated in mass to charge selection and ion fragmentation modes. Individual multipole ion guides are mounted in a linear assembly with no electrodes configured in between each multipole ion guide. At least a portion of each multipole ion guide mounted in a linear assembly resides in a vacuum region with higher background pressure. At least one ion guide (4) can be configured to extend continuously from one vaccum stage (72) into another (73). Individual sets of RF, +/- DC and secular frequency voltage supplies provide potentials to the rods of each multipole ion guide allowing the operation of ion transmission, ion trapping, mass to charge selection and ion fragmentation functions independently in each ion guide. The presence of higher background pressure along a portion of the multiple ion guide linear assembly allows the Collisional Induced Dissociation (CID) fragmentation of ions by axially accelerating ions from one multipole ion guide to an adjacent ion guide, analogous to a triple quadrupole function. Alternatively ions can be fragmented in one or more multipole ion guides using resonant frequency excitation CID, similar to ion fragmentation operation in three dimensional quadrupole ion traps.
IPC 1-7
IPC 8 full level
H01J 49/40 (2006.01); H01J 49/42 (2006.01)
CPC (source: EP)
H01J 49/004 (2013.01); H01J 49/063 (2013.01); H01J 49/4225 (2013.01)
Citation (search report)
- [XA] US 5652427 A 19970729 - WHITEHOUSE CRAIG M [US], et al
- See references of WO 9938193A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9938193 A1 19990729; AT E535008 T1 20111215; AU 2334199 A 19990809; CA 2318855 A1 19990729; CA 2318855 C 20060711; EP 1057209 A1 20001206; EP 1057209 A4 20060201; EP 1057209 B1 20111123; JP 2002502085 A 20020122
DOCDB simple family (application)
US 9901335 W 19990122; AT 99903281 T 19990122; AU 2334199 A 19990122; CA 2318855 A 19990122; EP 99903281 A 19990122; JP 2000528994 A 19990122