Global patent index - EP 1058539 A1

EP 1058539 A1 2000-12-13 - METHOD OF PREPARING PHARMACEUTICAL ACTIVE INGREDIENT COMPRISING WATER-INSOLUBLE DRUG AND PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION COMPRISING THE SAME

Title (en)

METHOD OF PREPARING PHARMACEUTICAL ACTIVE INGREDIENT COMPRISING WATER-INSOLUBLE DRUG AND PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION COMPRISING THE SAME

Title (de)

METHODE ZUR HERSTELLUNG EINES PHARMAZEUTISCH AKTIVEN BESTANDTEILS BEINHALTEND EINEN WASSERUNLÖSLICHEN WIRKSTOFF SOWIE EINE PHARMAZEUTISCHE ZUSAMMENSETZUNG ZUR ORALEN VERABREICHUNG DIE DIESEN BESTANDTEIL ENTHÄLT

Title (fr)

PROCEDE DE PREPARATION D'UN PRINCIPE ACTIF PHARMACEUTIQUE CONTENANT UN MEDICAMENT NON HYDROSOLUBLE ET COMPOSITION PHARMACEUTIQUE POUR L'ADMINISTRATION ORALE CONTENANT LEDIT PRINCIPE

Publication

EP 1058539 A1 (EN)

Application

EP 99901236 A

Priority

KR 9900025 W

Abstract (en)

[origin: WO0040220A1] A method of preparing a pharmaceutical active ingredient comprising a water-insoluble drug is provided. In the method, a water-insoluble drug in an organic solvent is mixed with a water-soluble polymer in an aqueous solvent and spray-dried. Thereafter, the drug microparticles is mixed with oil. The method can easily prepare a pharmaceutical active ingredient including water-insoluble drug, exhibiting good bioavailability. Accordingly, it is not required for specific technology in the preparation.

IPC 1-7 (main, further and additional classification)

A61K 9/14; A61K 38/13; A61K 47/30; A61K 47/44

IPC 8 full level (invention and additional information)

A61K 47/32 (2006.01); A61K 9/14 (2006.01); A61K 9/16 (2006.01); A61K 9/48 (2006.01); A61K 31/192 (2006.01); A61K 31/352 (2006.01); A61K 38/00 (2006.01); A61K 47/34 (2006.01); A61K 47/36 (2006.01); A61K 47/38 (2006.01); A61K 47/44 (2006.01)

CPC (invention and additional information)

A61K 9/4858 (2013.01); A61K 9/1652 (2013.01); A61K 9/1635 (2013.01); A61K 9/1641 (2013.01)

Citation (search report)

See references of WO 0040220A1

Designated contracting state (EPC)

DE

EPO simple patent family

WO 0040220 A1 20000713; EP 1058539 A1 20001213; JP 2002534371 A 20021015

INPADOC legal status

2003-08-06 [18D] DEEMED TO BE WITHDRAWN

- Ref Legal Event Code: 18D

- Effective date: 20030128

2002-10-30 [17Q] FIRST EXAMINATION REPORT

- Ref Legal Event Code: 17Q

- Effective date: 20020916

2000-12-13 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 20000712

2000-12-13 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): DE