EP 1058557 A1 20001213 - ENHANCEMENT OF IMMUNITY BY INTRANASAL INOCULATION OF IL-12
Title (en)
ENHANCEMENT OF IMMUNITY BY INTRANASAL INOCULATION OF IL-12
Title (de)
STEIGERUNG DER IMMUNITÄT DURCH INTRANASALE VERABREICHUNG VON IL-12
Title (fr)
RENFORCEMENT DE L'IMMUNITE PAR INOCULATION INTRA-NASALE D'IL-12
Publication
Application
Priority
- US 9904678 W 19990304
- US 3518898 A 19980305
Abstract (en)
[origin: WO9944635A1] The present invention relates to a method of enhancing an immune response to a pathogen in a host using intranasal administration of interleukin-12 (IL-12). In one embodiment, the present invention relates to a method of inducing an immune response to a pathogen in a host, which comprises administering intranasally to the host an effective amount of IL-12 and an antigen of the pathogen. In another embodiment, the present invention relates to a method of enhancing an immune response to a pathogen in a host, which comprises administering intranasally to the host an effective amount of IL-12 and an antigen of the pathogen. In a particular embodiment, the present invention relates to a method of inducing an immune response to a mucosal pathogen in a host, which comprises administering intranasally to the host an effective amount of IL-12 and an antigen of the pathogen. Also encompassed by the present invention is a method of inducing a Th1-like immune response to a pathogen in a host, comprising administering intranasally to the host an effective amount of IL-12 and an antigen of the pathogen. The present invention also relates to a method of enhancing a mucosal immune response to a pathogen in a host, which comprises administering intranasally to the host an effective amount of IL-12 and an antigen of the pathogen.
IPC 1-7
IPC 8 full level
A61K 9/00 (2006.01); A61K 38/00 (2006.01); A61K 39/002 (2006.01); A61K 39/02 (2006.01); A61K 39/12 (2006.01); A61K 39/145 (2006.01); A61K 39/39 (2006.01); A61P 31/00 (2006.01); A61P 33/00 (2006.01); A61P 37/04 (2006.01)
CPC (source: EP)
A61K 39/12 (2013.01); A61K 39/145 (2013.01); A61K 39/39 (2013.01); A61P 31/00 (2017.12); A61P 33/00 (2017.12); A61P 37/04 (2017.12); A61K 2039/543 (2013.01); A61K 2039/55538 (2013.01); A61K 2039/57 (2013.01); C12N 2760/16134 (2013.01); Y02A 50/30 (2017.12)
Citation (search report)
See references of WO 9944635A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9944635 A1 19990910; AU 2980899 A 19990920; AU 747917 B2 20020530; CA 2322337 A1 19990910; CN 1298307 A 20010606; EP 1058557 A1 20001213; JP 2002505302 A 20020219; NZ 506650 A 20031128
DOCDB simple family (application)
US 9904678 W 19990304; AU 2980899 A 19990304; CA 2322337 A 19990304; CN 99803679 A 19990304; EP 99911081 A 19990304; JP 2000534236 A 19990304; NZ 50665099 A 19990304