EP 1058560 A1 20001213 - TOPICAL OPHTHALMIC PREPARATIONS CONTAINING IMMUNOSUPPRESSIVE AGENTS
Title (en)
TOPICAL OPHTHALMIC PREPARATIONS CONTAINING IMMUNOSUPPRESSIVE AGENTS
Title (de)
TOPISCHE AUGENARZNEIMITTEL ENTHALTEND IMMUNOSUPPRESSIVA
Title (fr)
PREPARATIONS OPHTALMIQUES TOPIQUES CONTENANT DES AGENTS IMMUNOSUPPRESSEURS
Publication
Application
Priority
- CZ 9800054 W 19981217
- CZ 423797 A 19971230
Abstract (en)
[origin: WO9934830A1] Therapeutic preparations for topical ophthalmic application, containing from 0.02 to 5.0 weight % of immunosuppressive agents belonging to the groups of monocyclic undecapeptides, macrolide lactones or corticosteroids, in a vehicle comprising up to 10 weight % of polyalkyleneglycol-polyurethane copolymers. Said copolymers consist preferably of poly(oxy-1,2-ethanediyl)- alpha -hydro- omega -hydroxypolymers with 1,1'-methylene-bis-(4-isocyanatocyclohexane) having an average molecular weight of from 1000 to 3000 in a hydrophilic vehicle and preferably of poly[oxy(methyl-1,2-ethanediyl)]- alpha -hydro- omega -hydroxypolymers with 1,1'-methylene-bis-(4-isocyanatocyclohexane) having an average molecular weight of from 1600 to 18000 in a lipophilic vehicle. Said therapeutic agents can further contain additional excipients common in topical administration forms.
IPC 1-7
IPC 8 full level
A61K 9/00 (2006.01); A61K 9/08 (2006.01); A61K 9/10 (2006.01); A61K 31/436 (2006.01); A61K 31/573 (2006.01); A61K 31/585 (2006.01); A61K 38/00 (2006.01); A61K 38/13 (2006.01); A61K 47/34 (2017.01); A61P 27/02 (2006.01); A61P 37/06 (2006.01)
CPC (source: EP)
A61K 9/0048 (2013.01); A61K 47/34 (2013.01); A61P 27/02 (2018.01); A61P 37/06 (2018.01)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
WO 9934830 A1 19990715; AU 1481399 A 19990726; BG 104558 A 20010228; CA 2317010 A1 19990715; CZ 287497 B6 20001213; CZ 423797 A3 19990714; EP 1058560 A1 20001213; HR P20000258 A2 20010430; HU P0004173 A2 20010828; JP 2002500200 A 20020108; NO 20003344 D0 20000627; NO 20003344 L 20000627; PL 341604 A1 20010423; SK 171798 A3 19991008; SK 284246 B6 20041201
DOCDB simple family (application)
CZ 9800054 W 19981217; AU 1481399 A 19981217; BG 10455800 A 20000627; CA 2317010 A 19981217; CZ 423797 A 19971230; EP 98958793 A 19981217; HR P20000258 A 20000503; HU P0004173 A 19981217; JP 2000527277 A 19981217; NO 20003344 A 20000627; PL 34160498 A 19981217; SK 171798 A 19981214