Global Patent Index - EP 1059914 A2

EP 1059914 A2 2000-12-20 - METHOD FOR PRODUCING SOLID, SPHERICAL FORMS CONTAINING PHARMACEUTICAL ACTIVE AGENTS IN A BINDER MATRIX

Title (en)

METHOD FOR PRODUCING SOLID, SPHERICAL FORMS CONTAINING PHARMACEUTICAL ACTIVE AGENTS IN A BINDER MATRIX

Title (de)

VERFAHREN ZUR HERSTELLUNG VON FESTEN, SPHÄRISCHEN FORMKÖRPERN, ENTHALTEND PHARMAZEUTISCHE WIRKSTOFFE IN EINER BINDEMITTELMATRIX

Title (fr)

PROCEDE DE PRODUCTION DE CORPS MOULES SPHERIQUES SOLIDES CONTENANT DES PRINCIPES ACTIFS PHARMACEUTIQUES DANS UNE MATRICE CONSTITUEE D'UN LIANT

Publication

EP 1059914 A2 (DE)

Application

EP 99911718 A

Priority

  • DE 19809242 A
  • EP 9901271 W

Abstract (en)

[origin: DE19809242A1] The invention relates to a method for producing solid, spherical forms containing at least one pharmaceutical active agent homogeneously dispersed in an auxiliary matrix. According to this method, the constituents are mixed to form a melt which is then shaped. The invention is characterised in that at least one pharmaceutical active agent is processed with at least one thermoplastically processable matrix auxiliary to form a homogeneous melt with a viscosity of less than 5000 mPas and in that this melt is shaped into drops using a rotating perforated roll. These drops are then cooled so that they solidify.

IPC 1-7 (main, further and additional classification)

A61K 9/16

IPC 8 full level (invention and additional information)

A61K 9/16 (2006.01); A61K 31/135 (2006.01); A61K 31/192 (2006.01)

CPC (invention and additional information)

A61K 31/192 (2013.01); A61K 9/1623 (2013.01); A61K 9/1694 (2013.01); A61K 31/135 (2013.01)

Citation (search report)

See references of WO 9944588A3

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI NL PT SE

EPO simple patent family

DE 19809242 A1 19990909; CA 2322629 A1 19990910; EP 1059914 A2 20001220; WO 9944588 A2 19990910; WO 9944588 A3 19991028

INPADOC legal status


2002-10-30 [18W] WITHDRAWN

- Date of withdrawal: 20020905

2001-05-30 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20010412

2000-12-20 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000816

2000-12-20 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI NL PT SE