Global Patent Index - EP 1059922 A2

EP 1059922 A2 2000-12-20 - GLYCINE TRANSPORT INHIBITORS

Title (en)

GLYCINE TRANSPORT INHIBITORS

Title (de)

HEMMER DES GLYCINTRANSPORTS

Title (fr)

INHIBITEURS DU TRANSPORT DE LA GLYCINE

Publication

EP 1059922 A2 (EN)

Application

EP 99915541 A

Priority

  • EP 99915541 A
  • EP 9901309 W
  • EP 98200701 A

Abstract (en)

[origin: WO9944596A2] The present invention is concerned with the use of glycine transport inhibiting [4,4-bis(4-fluorophenyl)butyl]-1-(piperazinyl and piperidinyl) derivatives for the preparation of medicaments for treating disorders of the central and peripheral nervous system, in particular psychoses, pain, epilepsy, neurodegenerative diseases (Alzheimer's disease), stroke, head trauma, multiple sclerosis and the like. The invention further comprises novel compounds, their preparation and their pharmaceutical forms.

IPC 1-7 (main, further and additional classification)

A61K 31/445; A61K 31/495; C07D 211/58; C07D 333/22; C07D 401/04; C07D 401/06; C07D 471/04

IPC 8 full level (invention and additional information)

C07D 333/22 (2006.01); A61K 31/00 (2006.01); A61K 31/4427 (2006.01); A61K 31/445 (2006.01); A61K 31/4468 (2006.01); A61K 31/454 (2006.01); A61K 31/495 (2006.01); A61K 31/496 (2006.01); A61K 31/497 (2006.01); A61K 31/498 (2006.01); A61K 31/517 (2006.01); A61K 31/519 (2006.01); A61P 25/00 (2006.01); A61P 25/04 (2006.01); A61P 25/08 (2006.01); A61P 25/28 (2006.01); A61P 43/00 (2006.01); C07D 211/58 (2006.01); C07D 401/04 (2006.01); C07D 401/06 (2006.01); C07D 471/04 (2006.01)

CPC (invention and additional information)

A61K 31/00 (2013.01)

Citation (search report)

See references of WO 9944596A3

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

EPO simple patent family

WO 9944596 A2 19990910; WO 9944596 A3 20000217; AU 3408999 A 19990920; BG 104685 A 20010430; BR 9907951 A 20010130; CA 2322164 A1 19990910; CN 1292698 A 20010425; EE 200000482 A 20020215; EP 1059922 A2 20001220; HR P20000523 A2 20010228; HU 0101048 A2 20011028; IL 138228 D0 20011031; JP 2002505277 A 20020219; NO 20004431 A 20001030; NO 20004431 D0 20000905; PL 343435 A1 20010813; SK 13082000 A3 20010312; TR 200002567 T2 20001121

INPADOC legal status


2007-10-05 [REG HK WD] APPLICATIONS WITHDRAWN, DEEMED TO BE WITHDRAWN, OR REFUSED AFTER PUBLICATION IN HONG KONG

- Document: HK 1031833

2003-03-12 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20020902

2000-12-20 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20001006

2000-12-20 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

2000-12-20 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Free text: LT PAYMENT 20001006;LV PAYMENT 20001006;MK PAYMENT 20001006;RO PAYMENT 20001006;SI PAYMENT 20001006