EP 1060166 A1 20001220 - FIVE-MEMBERED, BENZO-CONDENSED HETEROCYCLES USED AS ANTITHROMBOTIC AGENTS
Title (en)
FIVE-MEMBERED, BENZO-CONDENSED HETEROCYCLES USED AS ANTITHROMBOTIC AGENTS
Title (de)
5-GLIEDRIGE BENZOKONDENSIERTE HETEROCYCLEN ALS ANTITHROMBOTIKA
Title (fr)
HETEROCYCLES BENZO CONDENSES A 5 CHAINONS UTILISES COMME AGENTS ANTITHROMBOTIQUES
Publication
Application
Priority
- DE 19804085 A 19980203
- DE 19834325 A 19980730
- EP 9900537 W 19990128
Abstract (en)
[origin: WO9940072A1] The invention relates to new five-membered, heterocyclic condensed benzoderivatives of the general formula (I), in which Ra to Rc, A, Ar, X and Y have the meanings assigned in claim 1, and their tautomers, stereoisomers, mixtures and salts, especially their physiologically compatible salts with inorganic or organic acids or bases, which have valuable properties. The compounds of the general formula (I) above, in which Rc is a cyano group, present valuable intermediate products for the production of the remaining compounds of the general formula (I), and the compounds of the above general formula (I), in which Rc is one of the following amidino groups, as well as their tautomers and stereoisomers, have valuable pharmacological properties, especially an antithrombotic activity.
IPC 1-7
C07D 235/16; A61K 31/415; C07D 403/12; C07D 413/14; C07D 401/06; C07D 413/06; C07D 401/12; C07D 403/14; C07D 263/56; C07D 277/64; C07D 209/18; C07D 307/81; C07D 405/12; C07D 405/14; C07F 9/32
IPC 8 full level
A61K 31/403 (2006.01); A61K 31/404 (2006.01); A61K 31/415 (2006.01); A61K 31/4164 (2006.01); A61K 31/4184 (2006.01); A61K 31/423 (2006.01); A61K 31/428 (2006.01); A61K 31/4427 (2006.01); A61K 31/443 (2006.01); A61K 31/4439 (2006.01); A61K 31/454 (2006.01); A61K 31/4709 (2006.01); A61K 31/4725 (2006.01); A61K 31/496 (2006.01); A61K 31/502 (2006.01); A61K 31/5355 (2006.01); A61K 31/5377 (2006.01); A61P 7/02 (2006.01); A61P 9/10 (2006.01); C07D 209/14 (2006.01); C07D 209/24 (2006.01); C07D 235/16 (2006.01); C07D 263/56 (2006.01); C07D 277/28 (2006.01); C07D 277/64 (2006.01); C07D 277/66 (2006.01); C07D 307/81 (2006.01); C07D 401/04 (2006.01); C07D 401/06 (2006.01); C07D 401/08 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 403/04 (2006.01); C07D 403/06 (2006.01); C07D 403/08 (2006.01); C07D 403/12 (2006.01); C07D 403/14 (2006.01); C07D 405/12 (2006.01); C07D 405/14 (2006.01); C07D 417/12 (2006.01); C07F 9/32 (2006.01); C07F 9/6506 (2006.01)
CPC (source: EP)
A61P 7/02 (2017.12); A61P 9/10 (2017.12); C07D 209/24 (2013.01); C07D 235/16 (2013.01); C07D 263/56 (2013.01); C07D 277/64 (2013.01); C07D 401/06 (2013.01); C07D 401/08 (2013.01); C07D 401/12 (2013.01); C07D 403/04 (2013.01); C07D 403/08 (2013.01); C07D 403/12 (2013.01); C07D 405/12 (2013.01); C07D 417/12 (2013.01); C07F 9/65068 (2013.01)
Citation (search report)
See references of WO 9940072A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9940072 A1 19990812; AU 2720199 A 19990823; CA 2319494 A1 19990812; EP 1060166 A1 20001220; JP 2002502844 A 20020129
DOCDB simple family (application)
EP 9900537 W 19990128; AU 2720199 A 19990128; CA 2319494 A 19990128; EP 99907437 A 19990128; JP 2000530502 A 19990128