EP 1060179 A1 20001220 - SUBSTITUTED AMINOMETHYL ISOXAZOLINE DERIVATIVES USEFUL AS ANTIMICROBIALS
Title (en)
SUBSTITUTED AMINOMETHYL ISOXAZOLINE DERIVATIVES USEFUL AS ANTIMICROBIALS
Title (de)
SUBSTITUIERTE AMINOMETHYL ISOXAZOLIN DERIVATE VERWENDBAR ALS ANTIMIKROBIELLE MITTEL
Title (fr)
DERIVES D'ISOXAZOLINE AMINOMETHYLE SUBSTITUES UTILES EN TANT QU'AGENTS ANTIMICROBIENS
Publication
Application
Priority
- US 9904262 W 19990210
- US 7591498 P 19980225
Abstract (en)
[origin: WO9943671A1] The present invention provides novel substituted aminoheteroaromatic isoxazoline derivatives of formula (I), wherein R1 is H, alkyl, cycloalkyl, alkoxy, amino, or alkylamino; Y is H, F, or CH3; W is O, or S; Ring P is a 5-membered heteroaromatic moiety having one to three atoms selected from the group consisting of sulfur, nitrogen and oxygen atoms, wherein the 5-membered heteroaromatic moiety can additionally have a fused-on benzene or naphthyl, a 6-membered heteroaromatic moiety having at least one nitrogen atom, wherein the 6-membered heteroaromatic moiety can additionally have a fused-on benzene, naphthyl or 5-membered heteroaromatic moiety having one to three atoms selected from the group consisting of sulfur, nitrogen and oxygen atoms; Q is a 4-, 5-, 6-, 7-, or 9-membered heterocyclic moiety containing one or more nitrogen, sulfur and/or oxygen. The compounds of the invention have high antimicrobial activity for preventing and treating infectious diseases.
IPC 1-7
IPC 8 full level
A61K 31/42 (2006.01); A61K 31/4355 (2006.01); A61K 31/4439 (2006.01); A61K 31/4545 (2006.01); A61K 31/496 (2006.01); A61K 31/5377 (2006.01); A61K 31/55 (2006.01); A61P 31/04 (2006.01); C07D 261/04 (2006.01); C07D 413/04 (2006.01); C07D 413/14 (2006.01); C07D 471/04 (2006.01); C07D 491/04 (2006.01); C07D 491/048 (2006.01)
CPC (source: EP)
A61P 31/04 (2017.12); C07D 491/04 (2013.01)
Citation (search report)
See references of WO 9943671A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9943671 A1 19990902; AU 3180999 A 19990915; CA 2318762 A1 19990902; EP 1060179 A1 20001220; JP 2002504550 A 20020212
DOCDB simple family (application)
US 9904262 W 19990210; AU 3180999 A 19990210; CA 2318762 A 19990210; EP 99913819 A 19990210; JP 2000533427 A 19990210