Global Patent Index - EP 1060179 A1

EP 1060179 A1 2000-12-20 - SUBSTITUTED AMINOMETHYL ISOXAZOLINE DERIVATIVES USEFUL AS ANTIMICROBIALS

Title (en)

SUBSTITUTED AMINOMETHYL ISOXAZOLINE DERIVATIVES USEFUL AS ANTIMICROBIALS

Title (de)

SUBSTITUIERTE AMINOMETHYL ISOXAZOLIN DERIVATE VERWENDBAR ALS ANTIMIKROBIELLE MITTEL

Title (fr)

DERIVES D'ISOXAZOLINE AMINOMETHYLE SUBSTITUES UTILES EN TANT QU'AGENTS ANTIMICROBIENS

Publication

EP 1060179 A1 (EN)

Application

EP 99913819 A

Priority

  • US 9904262 W
  • US 7591498 P

Abstract (en)

[origin: WO9943671A1] The present invention provides novel substituted aminoheteroaromatic isoxazoline derivatives of formula (I), wherein R1 is H, alkyl, cycloalkyl, alkoxy, amino, or alkylamino; Y is H, F, or CH3; W is O, or S; Ring P is a 5-membered heteroaromatic moiety having one to three atoms selected from the group consisting of sulfur, nitrogen and oxygen atoms, wherein the 5-membered heteroaromatic moiety can additionally have a fused-on benzene or naphthyl, a 6-membered heteroaromatic moiety having at least one nitrogen atom, wherein the 6-membered heteroaromatic moiety can additionally have a fused-on benzene, naphthyl or 5-membered heteroaromatic moiety having one to three atoms selected from the group consisting of sulfur, nitrogen and oxygen atoms; Q is a 4-, 5-, 6-, 7-, or 9-membered heterocyclic moiety containing one or more nitrogen, sulfur and/or oxygen. The compounds of the invention have high antimicrobial activity for preventing and treating infectious diseases.

IPC 1-7 (main, further and additional classification)

C07D 413/14; A61K 31/42; C07D 413/10; C07D 491/04

IPC 8 full level (invention and additional information)

C07D 491/048 (2006.01); A61K 31/42 (2006.01); A61K 31/4355 (2006.01); A61K 31/4439 (2006.01); A61K 31/4545 (2006.01); A61K 31/496 (2006.01); A61K 31/5377 (2006.01); A61K 31/55 (2006.01); A61P 31/04 (2006.01); C07D 261/04 (2006.01); C07D 413/04 (2006.01); C07D 413/14 (2006.01); C07D 471/04 (2006.01); C07D 491/04 (2006.01)

CPC (invention and additional information)

C07D 491/04 (2013.01)

Citation (search report)

See references of WO 9943671A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9943671 A1 19990902; AU 3180999 A 19990915; CA 2318762 A1 19990902; EP 1060179 A1 20001220; JP 2002504550 A 20020212

INPADOC legal status


2002-10-16 [18W] WITHDRAWN

- Date of withdrawal: 20020821

2000-12-20 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000913

2000-12-20 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2000-12-20 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Free text: AL PAYMENT 20000913;LT PAYMENT 20000913;LV PAYMENT 20000913;MK PAYMENT 20000913;RO PAYMENT 20000913;SI PAYMENT 20000913