Global Patent Index - EP 1061800 A4

EP 1061800 A4 20041006 - COMPOSITIONS AND METHODS FOR MODULATING VASCULARIZATION

Title (en)

COMPOSITIONS AND METHODS FOR MODULATING VASCULARIZATION

Title (de)

ZUSAMMENSETZUNGEN UND VERFAHREN ZUR MODULIERUNG DER VASKULARISATION

Title (fr)

COMPOSITIONS ET METHODES MODULANT LA VASCULARISATION

Publication

EP 1061800 A4 20041006 (EN)

Application

EP 99912344 A 19990309

Priority

  • US 9905130 W 19990309
  • US 7726298 P 19980309

Abstract (en)

[origin: WO9945775A1] The present invention generally provides methods for modulating formation of new blood vessels. In one embodiment, the methods include administering to a mammal an effective amount of granulocyte macrophage-colony stimulating factor (GM-CSF) sufficient to form the new blood vessels. Additionally provided are methods for preventing or reducing the severity of blood vessel damage in a mammal which methods preferably include administering to the mammal an effective amount of GM-CSF. Provided also as part of this invention are pharmaceutical products and kits for inducing formation of new blood vessels in the mammal.

IPC 1-7

A01N 37/18; C12Q 1/00; A61K 38/18; A61K 38/19; A61K 35/14; A61K 35/28

IPC 8 full level

A61K 35/44 (2015.01); A61K 38/00 (2006.01); A61K 38/18 (2006.01); A61K 38/19 (2006.01); A61K 38/22 (2006.01); A61K 38/30 (2006.01); A61K 38/44 (2006.01); A61K 45/00 (2006.01); A61P 9/00 (2006.01); A61P 43/00 (2006.01); C12Q 1/02 (2006.01); G01N 33/569 (2006.01)

CPC (source: EP)

A61K 35/44 (2013.01); A61K 38/1866 (2013.01); A61K 38/193 (2013.01); A61P 9/00 (2017.12); A61P 9/10 (2017.12); A61P 43/00 (2017.12); G01N 33/56972 (2013.01)

Citation (search report)

  • [PXPY] WO 9819712 A1 19980514 - ST ELIZABETHS MEDICAL CT [US]
  • [Y] FLAMME INGO ET AL: "Induction of vasculogenesis and hematopoiesis in vitro", DEVELOPMENT (CAMBRIDGE), vol. 116, no. 2, 1992, pages 435 - 439, XP002291992, ISSN: 0950-1991
  • [Y] ASAHARA TAKAYUKI ET AL: "Vasculogenesis, developed by endothelial progenitor cells, has significant role in neovascularization in severe ischemia", CIRCULATION, vol. 96, no. 8 SUPPL., 21 October 1997 (1997-10-21), & 70TH SCIENTIFIC SESSIONS OF THE AMERICAN HEART ASSOCIATION; ORLANDO, FLORIDA, USA; NOVEMBER 9-12, 1997, pages I415 - I416, XP008033796, ISSN: 0009-7322
  • [T] KALKA C ET AL: "Angiogenese und Vaskulogenese", HERZ, URBAN UND VOGEL, MUENCHEN, DE, vol. 25, no. 6, 2000, pages 611 - 622, XP002971995, ISSN: 0340-9937
  • See references of WO 9945775A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9945775 A1 19990916; AU 3073799 A 19990927; AU 766238 B2 20031009; CA 2322559 A1 19990916; CA 2322559 C 20120717; EP 1061800 A1 20001227; EP 1061800 A4 20041006; JP 2002506008 A 20020226; JP 2010265301 A 20101125

DOCDB simple family (application)

US 9905130 W 19990309; AU 3073799 A 19990309; CA 2322559 A 19990309; EP 99912344 A 19990309; JP 2000535201 A 19990309; JP 2010157554 A 20100712