Global Patent Index - EP 1061866 A1

EP 1061866 A1 2000-12-27 - BONE XENOGRAFTS

Title (en)

BONE XENOGRAFTS

Title (de)

KNOCHENXENOTRANSPLANTATE

Title (fr)

XENOGREFFES OSSEUSES

Publication

EP 1061866 A1 (EN)

Application

EP 99913897 A

Priority

  • US 9905661 W
  • US 7813998 P
  • US 10075598 P

Abstract (en)

[origin: WO9947080A1] The invention provides an article of manufacture comprising a substantially non-immunogenic bone xenograft for implantation into humans. The invention further provides a method for preparing a bone xenograft by removing at least a portion of a bone from a non-human animal to provide a xenograft (X); washing the xenograft in saline and alcohol; subjecting the xenograft to a cellular disruption treatment; and treating the xenograft with a glycosidase to remove surface carbohydrate moieties. The invention also provides an article of manufacture produced by the above identified method of invention. The invention further provides a bone xenograft for implantation into a human including a portion (10) of a bone from a nonhuman animal, wherein the portion has substantially no surface carbohydrate moieties which are susceptible to glycosidase digestion. Each xenograft of the invention has substantially the same mechanical properties as a corresponding native bone.

IPC 1-7 (main, further and additional classification)

A61F 2/28

IPC 8 full level (invention and additional information)

A61F 2/28 (2006.01); A61L 27/36 (2006.01); A61F 2/30 (2006.01)

CPC (invention and additional information)

A61L 27/3691 (2013.01); A61F 2/28 (2013.01); A61L 27/3608 (2013.01); A61L 27/365 (2013.01); A61L 27/3687 (2013.01); A61F 2/3094 (2013.01); A61F 2002/2835 (2013.01)

Combination set (CPC)

A61L 27/36 + A61L 2/204 + A61L 2/206

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9947080 A1 19990923; AU 3186899 A 19991011; AU 755316 B2 20021212; CA 2323866 A1 19990923; EP 1061866 A1 20001227; EP 1061866 A4 20030716; JP 2002506677 A 20020305

INPADOC legal status


2004-12-15 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20040615

2004-01-14 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20031202

2003-07-16 [A4] SUPPLEMENTARY SEARCH REPORT

- Effective date: 20030602

2003-07-16 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7A 61F 2/28 A

2003-07-16 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7A 61L 27/00 B

2000-12-27 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000925

2000-12-27 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE