Global Patent Index - EP 1061926 A2

EP 1061926 A2 2000-12-27 - HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE AS TACHYKININ RECEPTOR ANTAGONISTS

Title (en)

HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE AS TACHYKININ RECEPTOR ANTAGONISTS

Title (de)

HETEROZYKLISCHE VERBINDUNGEN, IHRE HERSTELLUNG UND IHRE VERWENDUNG ALS TACHYKININREZEPTORANTAGONISTEN

Title (fr)

COMPOSES HETEROCYCLIQUES, LEUR PRODUCTION ET LEUR UTILISATION

Publication

EP 1061926 A2 (EN)

Application

EP 99909233 A

Priority

  • JP 9901358 W
  • JP 6999998 A

Abstract (en)

[origin: WO9947132A2] A compound represented by formula (I), wherein ring M is a heterocyclic ring wherein formula (a) is one of -N=C<, -CO-N< or -CS-N<; R<a> and R<b> are bonded to each other to form Ring A, or they are the same or different and represent, independently, a hydrogen atom or a substituent on the Ring M; Ring A and Ring B represent, independently, an optionally substituted homocyclic or heterocyclic ring, with the proviso that at least one of them is an optionally substituted heterocyclic ring; Ring C is an optionally substituted homocyclic or heterocyclic ring; Ring Z is an optionally substituted nitrogen-containing heterocyclic ring; and n is an integer from 1 to 6, or a salt thereof has a tachykinin receptor antagonistic activity in vitro, and is useful for preventing or treating depression, anxiety, manic-depressive illness or psychopathy.

IPC 1-7 (main, further and additional classification)

A61K 31/55; A61K 31/435; C07D 471/04; C07D 471/14; C07D 487/04; C07D 498/04

IPC 8 full level (invention and additional information)

A61K 31/4375 (2006.01); A61K 31/55 (2006.01); A61K 31/551 (2006.01); A61P 1/00 (2006.01); A61P 1/08 (2006.01); A61P 11/06 (2006.01); A61P 11/14 (2006.01); A61P 13/00 (2006.01); A61P 19/02 (2006.01); A61P 25/18 (2006.01); A61P 25/22 (2006.01); A61P 25/24 (2006.01); A61P 29/00 (2006.01); A61P 43/00 (2006.01)

CPC (invention and additional information)

A61K 31/4375 (2013.01); A61K 31/55 (2013.01); A61K 31/551 (2013.01)

Citation (search report)

See references of WO 9947132A3

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9947132 A2 19990923; WO 9947132 A3 19991111; AR 018772 A1 20011212; AU 2853299 A 19991011; AU 751114 B2 20020808; BR 9908895 A 20001205; CA 2321155 A1 19990923; CN 1291099 A 20010411; EP 1061926 A2 20001227; EP 1184036 A2 20020306; HU 0100934 A2 20010928; HU 0100934 A3 20020930; ID 25818 A 20001109; IL 136950 D0 20010614; NO 20004144 A 20001010; NO 20004144 D0 20000818

INPADOC legal status


2002-11-27 [18W] WITHDRAWN

- Date of withdrawal: 20021008

2002-03-06 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20020121

2000-12-27 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000818

2000-12-27 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE