EP 1062207 A1 20001227 - 9-AMINOACRIDINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF
Title (en)
9-AMINOACRIDINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF
Title (de)
9-AMINOACRIDIN-DERIVATE UND VERFAHREN ZU IHRER HERSTELLUNG
Title (fr)
DERIVES 9-AMINOACRIDINE ET LEUR PROCESSUS DE PREPARATION
Publication
Application
Priority
- KR 9900787 W 19991217
- KR 19980056185 A 19981218
Abstract (en)
[origin: WO0037447A1] The present invention relates to new 9-aminoacridine derivatives of general formula (I), wherein A is hydrogen or (II) (wherein X is oxygen or sulfur, R1, R2, R3, R4 and R5 are independently hydrogen, halogen, nitro, amino, hydroxy, C1-C4 lower alkylhydroxy, C1-C4 lower alkylamino, C1-C8 alkyl, C1-C4 lower alkoxy or C1-C4 lower alkyloxycarbonyl and m and n are independently an integer of 0, 1 or 2), R6, R7, R8 and R9 are independently C1-C8 alkyl or C1-C4 lower alkoxy, and Y is hydrogen, amino, -N=CHR'(wherein R' is hydrogen, benzyl, C1-C8 alkyl or C1-C6 lower alkylamino), (III) (wherein R'' is hydrogen, benzyl, C1-C8 alkyl or C1-C6 lower alkylamino, and R''' is hydrogen, benzyl, C1-C8 alkyl or amino protecting group) or (IV) (wherein, X is as defined above, R1', R2', R3', R4' and R5' are independently hydrogen, halogen, nitro, amino, hydroxy, C1-C4 lower alkylhydroxy, C1-C4 lower alkylamino, C1-C8 alkyl, C1-C4 lower alkoxy or C1-C4 lower alkylcarboxy, and q and r are independently an integer of 0, 1 or 2) or its pharmaceutically acceptable salt, and process for the preparation thereof.
IPC 1-7
IPC 8 full level
A61K 31/473 (2006.01); A61P 35/00 (2006.01); C07D 219/04 (2006.01); C07D 219/10 (2006.01)
CPC (source: EP KR)
A61P 35/00 (2017.12 - EP); C07D 219/04 (2013.01 - KR); C07D 219/10 (2013.01 - EP); Y02P 20/55 (2015.11 - EP)
Citation (search report)
See references of WO 0037447A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0037447 A1 20000629; AU 1695000 A 20000712; AU 760138 B2 20030508; CA 2321143 A1 20000629; CN 1113871 C 20030709; CN 1291189 A 20010411; DE 69940914 D1 20090702; EP 1062207 A1 20001227; EP 1380574 A1 20040114; EP 1380574 B1 20090520; JP 2002533328 A 20021008; JP 3712361 B2 20051102; KR 100395143 B1 20030821; KR 20000040525 A 20000705; KR 20010041060 A 20010515
DOCDB simple family (application)
KR 9900787 W 19991217; AU 1695000 A 19991217; CA 2321143 A 19991217; CN 99803076 A 19991217; DE 69940914 T 19991217; EP 03077547 A 19991217; EP 99959999 A 19991217; JP 2000589519 A 19991217; KR 19980056185 A 19981218; KR 20007009097 A 20000818