Global patent index - EP 1062319 A1

EP 1062319 A1 2000-12-27 - VASCULAR ENDOTHELIAL GROWTH FACTOR 2

Title (en)

VASCULAR ENDOTHELIAL GROWTH FACTOR 2

Title (de)

VASKULÄRER , ENDOTHELSPEZIFISCHER WACHSTUMSFAKTOR

Title (fr)

FACTEUR DE CROISSANCE ENDOTHELIAL VASCULAIRE 2

Publication

EP 1062319 A1 (EN)

Application

EP 99912320 A

Priority

  • US 9905021 W
  • US 4210598 A
  • US 10799798 A

Abstract (en)

[origin: WO9946364A1] Disclosed are human VEGF-2 polypeptides, biologically active, diagnostically or therapeutically useful fragments, analogs, or derivatives thereof, and DNA(RNA) encoding such VEGF-2 polypeptides. Also provided are procedures for producing such polypeptides by recombinant techniques and antibodies and antagonists against such polypeptides. Such polypeptides and polynucleotides may be used therapeutically for stimulating wound healing and for vascular tissue repair. Also provided are methods of using the antibodies and antagonists to inhibit tumor angiogenesis and thus tumor growth, inflammation, diabetic retinopathy, rheumatoid arthritis, and psoriasis.

IPC 1-7 (main, further and additional classification)

C12N 1/21; A61K 38/18; C07K 14/50; C07K 16/22; C12N 5/10; C12N 15/18; C12N 15/63; C12Q 1/00; C12Q 1/68; C12Q 1/70

IPC 8 full level (invention and additional information)

C12N 15/09 (2006.01); A61K 38/22 (2006.01); A61K 48/00 (2006.01); A61P 9/10 (2006.01); A61P 9/12 (2006.01); A61P 17/06 (2006.01); A61P 19/02 (2006.01); C07K 14/50 (2006.01); C07K 14/52 (2006.01); C07K 16/22 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12Q 1/68 (2006.01); C12Q 1/70 (2006.01); A61K 38/00 (2006.01)

CPC (invention and additional information)

C07K 14/52 (2013.01); A61K 38/00 (2013.01)

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9946364 A1 19990916; WO 9946364 A9 19991118; AU 3072099 A 19990927; CA 2322748 A1 19990916; CN 1299407 A 20010613; EP 1062319 A1 20001227; EP 1062319 A4 20030423; JP 2002505873 A 20020226

INPADOC legal status

2006-04-26 [18D] DEEMED TO BE WITHDRAWN

- Ref Legal Event Code: 18D

- Effective date: 20051011

2005-07-27 [17Q] FIRST EXAMINATION REPORT

- Ref Legal Event Code: 17Q

- Effective date: 20050608

2003-04-23 [A4] SUPPLEMENTARY SEARCH REPORT

- Ref Legal Event Code: A4

- Effective date: 20030306

2000-12-27 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 20000929

2000-12-27 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE