EP 1062319 A1 20001227 - VASCULAR ENDOTHELIAL GROWTH FACTOR 2
Title (en)
VASCULAR ENDOTHELIAL GROWTH FACTOR 2
Title (de)
VASKULÄRER , ENDOTHELSPEZIFISCHER WACHSTUMSFAKTOR
Title (fr)
FACTEUR DE CROISSANCE ENDOTHELIAL VASCULAIRE 2
Publication
Application
Priority
- US 9905021 W 19990310
- US 4210598 A 19980313
- US 10799798 A 19980630
Abstract (en)
[origin: WO9946364A1] Disclosed are human VEGF-2 polypeptides, biologically active, diagnostically or therapeutically useful fragments, analogs, or derivatives thereof, and DNA(RNA) encoding such VEGF-2 polypeptides. Also provided are procedures for producing such polypeptides by recombinant techniques and antibodies and antagonists against such polypeptides. Such polypeptides and polynucleotides may be used therapeutically for stimulating wound healing and for vascular tissue repair. Also provided are methods of using the antibodies and antagonists to inhibit tumor angiogenesis and thus tumor growth, inflammation, diabetic retinopathy, rheumatoid arthritis, and psoriasis.
IPC 1-7
C12N 1/21; C12N 5/10; C12N 15/18; C12N 15/63; C12Q 1/00; C12Q 1/68; C12Q 1/70; A61K 38/18; C07K 14/50; C07K 16/22
IPC 8 full level
C12N 15/09 (2006.01); A61K 38/22 (2006.01); A61K 48/00 (2006.01); A61P 9/10 (2006.01); A61P 9/12 (2006.01); A61P 17/06 (2006.01); A61P 19/02 (2006.01); C07K 14/50 (2006.01); C07K 14/52 (2006.01); C07K 16/22 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12Q 1/68 (2006.01); C12Q 1/70 (2006.01); A61K 38/00 (2006.01)
CPC (source: EP KR)
A61P 9/10 (2017.12 - EP); A61P 9/12 (2017.12 - EP); A61P 17/06 (2017.12 - EP); A61P 19/02 (2017.12 - EP); C07K 14/52 (2013.01 - EP); C12N 1/20 (2013.01 - KR); A61K 38/00 (2013.01 - EP)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9946364 A1 19990916; WO 9946364 A9 19991118; AU 3072099 A 19990927; CA 2322748 A1 19990916; CN 1299407 A 20010613; EP 1062319 A1 20001227; EP 1062319 A4 20030423; JP 2002505873 A 20020226; KR 20010034576 A 20010425
DOCDB simple family (application)
US 9905021 W 19990310; AU 3072099 A 19990310; CA 2322748 A 19990310; CN 99805771 A 19990310; EP 99912320 A 19990310; JP 2000535731 A 19990310; KR 20007010016 A 20000908