Global Patent Index - EP 1062363 A1

EP 1062363 A1 2000-12-27 - METHOD FOR PRODUCING AGENTS FOR TREATING TUMOUR DISEASES AND FOR IMMUNOSUPPRESSION

Title (en)

METHOD FOR PRODUCING AGENTS FOR TREATING TUMOUR DISEASES AND FOR IMMUNOSUPPRESSION

Title (de)

VERFAHREN ZUR HERSTELLUNG VON MITTELN ZUR BEHANDLUNG VON TUMORERKRANKUNGEN UND ZUR IMMUNSUPPRESSION

Title (fr)

PROCEDE DE PRODUCTION D'AGENTS POUR LE TRAITEMENT DE MALADIES TUMORALES ET POUR L'IMMUNODEPRESSION

Publication

EP 1062363 A1 (DE)

Application

EP 99907563 A

Priority

  • DE 19811326 A
  • EP 9901205 W

Abstract (en)

[origin: DE19811326C1] The preparation of agents for the treatment of tumor diseases and immuno-suppression comprises contacting chemical test substances with target cells expressing Ah-receptors. The binding of the test substance to the receptor is measured by the binding-induced expression of a detector gene. Test substances that bind the Ah-receptor are then used in the preparation of the therapeutic agent. Independent claims are also included for the following: (1) transgenic target cells used in the preparation process above, comprising a genome containing a foreign detector gene under the control of the Kip1-promoter; (2) chemical compounds identified as Ah-receptor-binding substances by the method above; (3) a therapeutic agent comprising the chemical compounds of (2); (4) the use of the therapeutic agent of (3) for the treatment of tumor diseases and for immuno-suppression.

IPC 1-7 (main, further and additional classification)

C12Q 1/68

IPC 8 full level (invention and additional information)

C12N 15/09 (2006.01); A61K 45/00 (2006.01); A61P 35/00 (2006.01); A61P 37/06 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12Q 1/68 (2006.01)

CPC (invention and additional information)

C12Q 1/6897 (2013.01); A01K 2217/05 (2013.01)

Citation (search report)

See references of WO 9947703A1

Designated contracting state (EPC)

AT BE CH FR GB IT LI NL

EPO simple patent family

DE 19811326 C1 19990826; EP 1062363 A1 20001227; JP 2002506657 A 20020305; US 6482610 B1 20021119; WO 9947703 A1 19990923

INPADOC legal status


2011-08-31 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20110224

2009-12-09 [RAP1] TRANSFER OF RIGHTS OF AN EP PUBLISHED APPLICATION

- Owner name: KARLSRUHER INSTITUT FUER TECHNOLOGIE

2007-05-02 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20050311

2007-01-10 [RIN1] INVENTOR (CORRECTION)

- Inventor name: GOETTLICHER, MARTIN

2007-01-10 [RIN1] INVENTOR (CORRECTION)

- Inventor name: KOLLURI, SIVA, KUMAR

2007-01-10 [RIN1] INVENTOR (CORRECTION)

- Inventor name: WEISS, CARSTEN

2006-09-06 [RIN1] INVENTOR (CORRECTION)

- Inventor name: GOETTLICHER, MARTIN

2006-09-06 [RIN1] INVENTOR (CORRECTION)

- Inventor name: KOLLURI, SIVA, KUMAR

2006-09-06 [RIN1] INVENTOR (CORRECTION)

- Inventor name: WEISS, CARSTEN

2005-04-27 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20050311

2000-12-27 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000731

2000-12-27 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH FR GB IT LI NL