Global Patent Index - EP 1062368 A1

EP 1062368 A1 2000-12-27 - PROTEIN INTERACTION AND TRANSCRIPTION FACTOR TRAP

Title (en)

PROTEIN INTERACTION AND TRANSCRIPTION FACTOR TRAP

Title (de)

PROTEIN INTERAKTIONS UND TRANSKRIPTIONSFAKTOR FALLE

Title (fr)

DETECTION DE L'INTERACTION DE PROTEINES ET PIEGEAGE DU FACTEUR DE TRANSCRIPTION

Publication

EP 1062368 A1 (EN)

Application

EP 99936098 A

Priority

  • CA 9900173 W
  • CA 2224475 A

Abstract (en)

[origin: WO9943848A1] Methods are provided which make use of a combination of gene trap and two-hybrid methodologies for the identification and characterization of unknown genes according to protein-protein interactions of the gene product or for the identification and characterization of unknown genes encoding transcriptional activator domains (AD). Interaction of an exon-encoded protein domain with a known protein, or functioning of the exon-encoded domain as an AD, is detected by reconstituting the activity of a transcriptional activator. Suitable gene trap vectors are also provided.

IPC 1-7 (main, further and additional classification)

C12Q 1/68; C12N 15/10; C12N 15/62; C12N 15/85

IPC 8 full level (invention and additional information)

C12N 15/10 (2006.01); C12N 15/62 (2006.01); C12N 15/85 (2006.01); C12Q 1/68 (2006.01)

CPC (invention and additional information)

C12Q 1/6897 (2013.01); C12N 15/1055 (2013.01); C12N 15/625 (2013.01); C12N 15/85 (2013.01); C07K 2319/61 (2013.01); C07K 2319/71 (2013.01); C07K 2319/81 (2013.01); C12N 2800/40 (2013.01); C12N 2800/60 (2013.01); C12N 2840/44 (2013.01)

Combination set (CPC)

C12Q 1/6897 + C12Q 2565/201

Citation (search report)

See references of WO 9943848A1

Designated contracting state (EPC)

AT BE CH DE DK FR GB IT LI NL SE

EPO simple patent family

WO 9943848 A1 19990902; CA 2224475 A1 19990825; EP 1062368 A1 20001227

INPADOC legal status


2005-03-09 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20040831

2000-12-27 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000925

2000-12-27 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH DE DK FR GB IT LI NL SE