Global Patent Index - EP 1062509 A2

EP 1062509 A2 20001227 - METHODS AND COMPOSITIONS FOR DIAGNOSIS OF RHEUMATOID ARTHRITIS

Title (en)

METHODS AND COMPOSITIONS FOR DIAGNOSIS OF RHEUMATOID ARTHRITIS

Title (de)

VERFAHREN UND ZUSAMMENSETZUNGEN ZUR DIAGNOSE VON RHEUMATOIDER ARTHRITIS

Title (fr)

PROCEDES ET COMPOSITIONS POUR LE DIAGNOSTIC DE LA POLYARTHRITE RHUMATOIDE

Publication

EP 1062509 A2 20001227 (EN)

Application

EP 99910490 A 19990315

Priority

  • GB 9900763 W 19990315
  • GB 9805477 A 19980313

Abstract (en)

[origin: WO9947925A2] The present invention provides methods and compositions for screening, diagnosis and prognosis of RA, for monitoring the effectiveness of RA treatment, and for drug development. RA-Diagnostic Features (RADFs), detectable by two-dimensional electrophoresis of serum or plasma are described. The invention further provides RA-Diagnostic Protein Isoforms (RPIs) detectable in synovial fluid, serum or plasma, preparations comprising isolated RPIs, antibodies immunospecific for RPIs, and kits comprising the aforesaid.

IPC 1-7

G01N 33/53

IPC 8 full level

A61K 31/70 (2006.01); A61K 38/00 (2006.01); A61K 39/00 (2006.01); A61K 39/395 (2006.01); C07K 14/47 (2006.01); C07K 16/18 (2006.01); G01N 27/447 (2006.01); G01N 33/15 (2006.01); G01N 33/50 (2006.01); G01N 33/564 (2006.01); G01N 33/68 (2006.01)

CPC (source: EP)

A61K 39/0008 (2013.01); C07K 14/47 (2013.01); C07K 14/4713 (2013.01); G01N 33/564 (2013.01); A61K 38/00 (2013.01); A61K 2039/505 (2013.01); G01N 2800/102 (2013.01)

Citation (search report)

See references of WO 9947925A2

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9947925 A2 19990923; WO 9947925 A3 19991125; AU 2942999 A 19991011; AU 756588 B2 20030116; CA 2323238 A1 19990923; CN 1300367 A 20010620; EP 1062509 A2 20001227; GB 9805477 D0 19980513; JP 2002507723 A 20020312; ZA 992079 B 20001010

DOCDB simple family (application)

GB 9900763 W 19990315; AU 2942999 A 19990315; CA 2323238 A 19990315; CN 99806001 A 19990315; EP 99910490 A 19990315; GB 9805477 A 19980313; JP 2000537069 A 19990315; ZA 992079 A 19990315