EP 1063891 A2 20010103 - METHODS FOR ENHANCED ANTIGEN PRESENTATION ON ANTIGEN-PRESENTING CELLS AND COMPOSITIONS PRODUCED THEREBY
Title (en)
METHODS FOR ENHANCED ANTIGEN PRESENTATION ON ANTIGEN-PRESENTING CELLS AND COMPOSITIONS PRODUCED THEREBY
Title (de)
METHODEN ZUR GESTEIGERTEN ANTIGEN PRÄSENTATION AUF ANTIGEN-PRÄSENTIERENDEN ZELLEN UND DADURCH HERGESTELLTE ZUBEREITUNGEN
Title (fr)
METHODES POUR UNE PRESENTATION AMELIOREE DE L'ANTIGENE SUR DES CELLULES PRESENTATRICES DE L'ANTIGENE, ET COMPOSITIONS PRODUITES SELON CES METHODES
Publication
Application
Priority
- US 9906031 W 19990319
- US 7888098 P 19980320
Abstract (en)
[origin: WO9947102A2] The present invention provides compositions and methods for immunotherapy, and in particular for inducing an immune response against an antigen in a patient. Thus, in one aspect, this invention provides genetically modified antigen-presenting cells which are more potent presenters of exogenous peptide than parental antigen-presenting cells. Compositions comprising these genetically modified cells and a carrier, such as pharmaceutically acceptable carrier, are further provided by this invention. The genetically modified antigen-presenting cells of this invention can be used in adoptive immunotherapy or to expand a substantially pure population of immune effector cells. Methods for expansion of the substantially pure population of cells are also provided by this invention.
IPC 1-7
A01N 63/00; C12N 5/06; C12N 5/10; C12N 15/63; C12N 15/86; C07H 21/04
IPC 8 full level
C12N 15/09 (2006.01); A61K 35/26 (2006.01); A61K 35/28 (2006.01); A61K 48/00 (2006.01); A61P 37/02 (2006.01); A61P 37/04 (2006.01); C12N 5/0784 (2010.01); A61K 39/00 (2006.01)
CPC (source: EP US)
A61K 39/4615 (2023.05 - EP US); A61K 39/4622 (2023.05 - EP US); A61K 39/464492 (2023.05 - EP US); A61K 2239/31 (2023.05 - US); A61K 2239/38 (2023.05 - US); A61P 37/02 (2018.01 - EP); A61P 37/04 (2018.01 - EP); C12N 5/0639 (2013.01 - EP US); A61K 2239/31 (2023.05 - EP); A61K 2239/38 (2023.05 - EP); C12N 2510/00 (2013.01 - EP)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9947102 A2 19990923; WO 9947102 A3 19991021; AU 3102399 A 19991011; AU 755156 B2 20021205; CA 2322750 A1 19990923; EP 1063891 A2 20010103; EP 1063891 A4 20021023; JP 2002506622 A 20020305
DOCDB simple family (application)
US 9906031 W 19990319; AU 3102399 A 19990319; CA 2322750 A 19990319; EP 99912710 A 19990319; JP 2000536343 A 19990319