Global Patent Index - EP 1063891 A2

EP 1063891 A2 2001-01-03 - METHODS FOR ENHANCED ANTIGEN PRESENTATION ON ANTIGEN-PRESENTING CELLS AND COMPOSITIONS PRODUCED THEREBY

Title (en)

METHODS FOR ENHANCED ANTIGEN PRESENTATION ON ANTIGEN-PRESENTING CELLS AND COMPOSITIONS PRODUCED THEREBY

Title (de)

METHODEN ZUR GESTEIGERTEN ANTIGEN PRÄSENTATION AUF ANTIGEN-PRÄSENTIERENDEN ZELLEN UND DADURCH HERGESTELLTE ZUBEREITUNGEN

Title (fr)

METHODES POUR UNE PRESENTATION AMELIOREE DE L'ANTIGENE SUR DES CELLULES PRESENTATRICES DE L'ANTIGENE, ET COMPOSITIONS PRODUITES SELON CES METHODES

Publication

EP 1063891 A2 (EN)

Application

EP 99912710 A

Priority

  • US 9906031 W
  • US 7888098 P

Abstract (en)

[origin: WO9947102A2] The present invention provides compositions and methods for immunotherapy, and in particular for inducing an immune response against an antigen in a patient. Thus, in one aspect, this invention provides genetically modified antigen-presenting cells which are more potent presenters of exogenous peptide than parental antigen-presenting cells. Compositions comprising these genetically modified cells and a carrier, such as pharmaceutically acceptable carrier, are further provided by this invention. The genetically modified antigen-presenting cells of this invention can be used in adoptive immunotherapy or to expand a substantially pure population of immune effector cells. Methods for expansion of the substantially pure population of cells are also provided by this invention.

IPC 1-7 (main, further and additional classification)

A01N 63/00; C07H 21/04; C12N 5/06; C12N 5/10; C12N 15/63; C12N 15/86

IPC 8 full level (invention and additional information)

C12N 15/09 (2006.01); A61K 35/26 (2006.01); A61K 35/28 (2006.01); A61K 48/00 (2006.01); A61P 37/02 (2006.01); A61P 37/04 (2006.01); C12N 5/0784 (2010.01)

CPC (invention and additional information)

C12N 5/0639 (2013.01); A61K 2039/5154 (2013.01); A61K 2039/5156 (2013.01); C12N 2510/00 (2013.01)

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9947102 A2 19990923; WO 9947102 A3 19991021; AU 3102399 A 19991011; AU 755156 B2 20021205; CA 2322750 A1 19990923; EP 1063891 A2 20010103; EP 1063891 A4 20021023; JP 2002506622 A 20020305

INPADOC legal status


2003-02-26 [18W] WITHDRAWN

- Effective date: 20021219

2002-10-23 [A4] SUPPLEMENTARY SEARCH REPORT

- Effective date: 20020911

2002-10-23 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A4

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2001-01-03 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000920

2001-01-03 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE