Title (en)

COMPOUNDS AND METHODS FOR USE IN TREATING NEOPLASIA, CANCER, HYPERPROLIFERATIVE CELL GROWTH AND CHRONIC INFLAMMATORY DISEASES

Title (de)

VERBINDUNGEN UND METHODEN ZUR VERWENDUNG IN DER BEHANDLUNG VON NEOPLASIEN, KREBS, HYPERPROLIFERATIVEM ZELLWACHSTUM UND CHRONISCH-INFLAMMATORISCHEN ERKRANKUNGEN

Title (fr)

COMPOSES ET METHODES DE TRAITEMENT DE LA NEOPLASIE, DU CANCER, DE LA CROISSANCE CELLULAIRE HYPERPROLIFERANTE, ET DE MALADIES INFLAMMATOIRES CHRONIQUES

Publication

EP 1063986 A1 20010103 (EN)

Application

EP 99908466 A 19990225

Priority

• US 9904114 W 19990225
• US 7587398 P 19980225

Abstract (en)

[origin: WO9943313A1] The present invention relates to a novel method for the treatment of neoplasia, including cancer and other diseases and conditions in humans and mammals. More particularly, in preferred aspects, the present invention provides a method for the use of a novel class of chemical agents, the 3H-1,2-Dithiolo[4,3-d]pyrimidin-5,7-diones and 4H-1,3-Dithiino[5,4-d]pyrimidin-8-one-7S-oxides and the respective nucleosides and nucleotides, for the treatment of both neoplasia, drug sensitive and drug-resistant breast, colon, ovarian and lung cancer, among others, hyperproliferative cell growth, chronic inflammatory diseases and viral and other microbial infections.

IPC 1-7

C07D 495/04; C07D 239/60; A61K 31/505; A61K 31/315; C07H 19/24

IPC 8 full level

C07D 239/60 (2006.01); C07D 495/04 (2006.01); C07H 19/23 (2006.01); C07H 19/24 (2006.01)

CPC (source: EP)

C07D 239/60 (2013.01); C07D 495/04 (2013.01); C07H 19/23 (2013.01); C07H 19/24 (2013.01)

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9943313 A1 19990902; AU 2789699 A 19990915; CA 2321715 A1 19990902; EP 1063986 A1 20010103; EP 1063986 A4 20040901

DOCDB simple family (application)

US 9904114 W 19990225; AU 2789699 A 19990225; CA 2321715 A 19990225; EP 99908466 A 19990225