Global Patent Index - EP 1063996 A1

EP 1063996 A1 2001-01-03 - PHARMACEUTICAL COMPOSITIONS CONTAINING IN COMBINATION TWO ANTAGONISTS SELECTIVE OF ARGININE-VASSOPRESSIN V RECEPTORS, EVEN OF V 1A? AND V 2? RECEPTORS

Title (en)

PHARMACEUTICAL COMPOSITIONS CONTAINING IN COMBINATION TWO ANTAGONISTS SELECTIVE OF ARGININE-VASSOPRESSIN V RECEPTORS, EVEN OF V 1A? AND V 2? RECEPTORS

Title (de)

ARZNEIMITTEL MIT ZWEI SELEKTIVEN HEMMERN DER ARGININ-VASOPRESSIN-V-REZEPTOREN, NÄMLICH DER REZEPTOREN V-1A UND V-2

Title (fr)

COMPOSITIONS PHARMACEUTIQUES CONTENANT EN ASSOCIATION DEUX ANTAGONISTES SELECTIFS DES RECEPTEURS V DE L'ARGININE-VASOPRESSINE, VOIR DES RECEPTEURS V-1A ET V-2

Publication

EP 1063996 A1 (FR)

Application

EP 99906313 A

Priority

  • FR 9900450 W
  • FR 9802874 A

Abstract (en)

[origin: FR2775598A1] The invention concerns pharmaceutical compositions containing in combination (2S)- 1-[(2R,3S)- 5-chloro-3-(2-chlorophenyl)-1- (3, 4-dimethoxybenzenesulphonyl)-3-hydroxy-2, 3-dihydro-1H-indole-2- (carbonyl]pyrrolidine-2-carboxamide, antagonist selective of V1a arginine-vasopressin receptors, with 1- [4-(N-tert-butylcarbamoyl)-2- methoxybenzenesulphonyl]-5-ethoxy-3-spiro[4- (2-morpholinoethyloxy)cyclohexane]indol-2-one, the equatorial isomer, or one of the salts thereof, antagonist selective of V2 arginine-vasopressin. The invention also concerns the use of said compositions for preparing medicines for treating all pathologies in which either arginine-vasopressin, or V2 receptors are involved.

IPC 1-7 (main, further and additional classification)

A61K 31/535

IPC 8 full level (invention and additional information)

C07D 403/06 (2006.01); A61K 31/403 (2006.01); A61K 31/404 (2006.01); A61K 31/535 (2006.01); A61K 31/5377 (2006.01); A61P 1/00 (2006.01); A61P 5/00 (2006.01); A61P 7/10 (2006.01); A61P 9/00 (2006.01); A61P 11/00 (2006.01); A61P 13/12 (2006.01); A61P 15/10 (2006.01); A61P 25/00 (2006.01); A61P 27/02 (2006.01); A61P 27/06 (2006.01); A61P 43/00 (2006.01); C07D 209/96 (2006.01)

CPC (invention and additional information)

A61K 31/535 (2013.01)

Combination set (CPC)

  1. A61K 31/535 + A61K 31/415 + A61K 31/40
  2. A61K 31/535 + A61K 31/40
  3. A61K 31/535 + A61K 2300/00

Citation (search report)

See references of WO 9944613A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

FR 2775598 A1 19990910; AR 016984 A1 20010801; AU 2629299 A 19990920; CO 5070635 A1 20010828; EP 1063996 A1 20010103; GT 199900027 A 20000819; JP 2002505289 A 20020219; US 6627649 B1 20030930; WO 9944613 A1 19990910; ZA 9901765 B 19990906

INPADOC legal status


2004-10-06 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20040217

2003-01-15 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20021129

2001-01-03 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20001006

2001-01-03 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2001-01-03 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Free text: AL PAYMENT 20001006;LT PAYMENT 20001006;LV PAYMENT 20001006;MK PAYMENT 20001006;RO PAYMENT 20001006;SI PAYMENT 20001006