Global Patent Index - EP 1064015 A2

EP 1064015 A2 2001-01-03 - RECEPTOR DERIVED PEPTIDES AS MODULATORS OF RECEPTOR ACTIVITY

Title (en)

RECEPTOR DERIVED PEPTIDES AS MODULATORS OF RECEPTOR ACTIVITY

Title (de)

VON REZEPTOREN ABGELEITETE PEPTIDE ALS MODULATOREN DER REZEPTORAKTIVITÄT

Title (fr)

PEPTIDES DERIVES DE RECEPTEURS AGISSANT EN TANT QUE MODULATEURS DE L'ACTIVITE DE CES RECEPTEURS

Publication

EP 1064015 A2 (EN)

Application

EP 99908383 A

Priority

  • US 9903910 W
  • US 2893898 A

Abstract (en)

[origin: WO9942127A2] Oligopeptides having an amino acid sequence corresponding to a receptor's extracellular domain, and having sequence similarity to regulatory peptides from MHC class I antigens, enhance or replace the physiological response of ligand binding to the corresponding receptor. The oligopeptides are used in diagnosis and therapy of diseases that involve inadequate or inappropriate receptor response as well as in the screening of drug candidates that affect surface expression of receptors. Also useful for drug screening is a modified receptor molecule, where the sequence corresponding to the regulatory peptide is modified or deleted.

IPC 1-7 (main, further and additional classification)

A61K 38/17; G01N 33/50

IPC 8 full level (invention and additional information)

G01N 33/50 (2006.01); A61K 38/00 (2006.01); A61K 38/17 (2006.01); A61P 3/10 (2006.01); A61P 5/50 (2006.01); A61P 43/00 (2006.01); C07K 14/705 (2006.01); C07K 14/72 (2006.01); C12N 15/09 (2006.01); G01N 33/15 (2006.01); G01N 33/566 (2006.01); G01N 33/68 (2006.01)

CPC (invention and additional information)

C07K 14/705 (2013.01); C07K 14/72 (2013.01); G01N 33/566 (2013.01); G01N 33/6869 (2013.01); A61K 38/00 (2013.01)

Citation (search report)

See references of WO 9942127A3

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9942127 A2 19990826; WO 9942127 A3 19991028; AU 2783099 A 19990906; CA 2322200 A1 19990826; EP 1064015 A2 20010103; JP 2002508160 A 20020319

INPADOC legal status


2006-03-15 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20050930

2001-02-28 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20010111

2001-01-03 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000925

2001-01-03 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE