Global Patent Index - EP 1064354 A1

EP 1064354 A1 2001-01-03 - COMPOSITIONS AND METHODS FOR GENE-BASED VACCINES TO PROVOKE T CELL RESPONSES

Title (en)

COMPOSITIONS AND METHODS FOR GENE-BASED VACCINES TO PROVOKE T CELL RESPONSES

Title (de)

ZUSAMMENSETZUNGEN UND VERFAHREN FÜR AUD GENEN BASIERENDE VAKZINE ZUM HERVORRUFEN VON T-Zell ANTWORTEN

Title (fr)

COMPOSITIONS ET METHODES POUR PROVOQUER UNE REPONSE DES CELLULES T PAR DES VACCINS A BASE DE GENES

Publication

EP 1064354 A1 (EN)

Application

EP 99912709 A

Priority

  • US 9906030 W
  • US 7872598 P

Abstract (en)

[origin: WO9947641A1] This invention provides a polynucleotide encoding an antigen that is processed and presented with an MHC Class I molecule on an antigen-presenting cell (APC) and an antigen that is processed and presented with an MHC Class II molecule on the APC. Compositions containing these polynucleotides are further provided by this invention. Methods of increasing presentation of a peptide on the surface of an APC, and APCs produced by the methods, are further provided. Also provided are diagnostic and immunomodulatory methods using polynucleotides, APCs, and immune effector cells of the invention.

IPC 1-7 (main, further and additional classification)

C12N 1/21; A61K 35/00; A61K 35/12; A61K 38/00; A61K 48/00; C07K 5/00; C12N 15/11; C12N 15/63; C12N 15/85; C12N 15/86

IPC 8 full level (invention and additional information)

C12N 15/09 (2006.01); A61K 31/711 (2006.01); A61K 35/12 (2006.01); A61K 38/00 (2006.01); A61K 39/00 (2006.01); A61K 48/00 (2006.01); A61P 37/04 (2006.01); C07K 5/00 (2006.01); C07K 14/47 (2006.01); C12N 1/21 (2006.01); C12N 5/06 (2006.01)

CPC (invention and additional information)

A61K 39/0011 (2013.01); C07K 14/4748 (2013.01); A61K 2039/51 (2013.01); A61K 2039/53 (2013.01)

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9947641 A1 19990923; AU 3102299 A 19991011; CA 2322659 A1 19990923; EP 1064354 A1 20010103; EP 1064354 A4 20020612; JP 2002506633 A 20020305

INPADOC legal status


2003-07-23 [18D] DEEMED TO BE WITHDRAWN

- Ref Legal Event Code: 18D

- Effective date: 20030121

2002-10-23 [17Q] FIRST EXAMINATION REPORT

- Ref Legal Event Code: 17Q

- Effective date: 20020910

2002-06-12 [A4] SUPPLEMENTARY SEARCH REPORT

- Ref Legal Event Code: A4

- Effective date: 20020429

2002-06-12 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2001-01-03 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 20000920

2001-01-03 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE