Global Patent Index - EP 1064373 A2

EP 1064373 A2 2001-01-03 - IDENTIFICATION OF FACTORS WHICH MEDIATE THE INTERACTION OF HETEROTRIMERIC G PROTEINS AND MONOMERIC G PROTEINS

Title (en)

IDENTIFICATION OF FACTORS WHICH MEDIATE THE INTERACTION OF HETEROTRIMERIC G PROTEINS AND MONOMERIC G PROTEINS

Title (de)

IDENTIFIZIERUNG VON FAKTOREN, DIE DIE INTERAKTION ZWISCHEN HETEROTRIMEREN UND MONOMEREN G PROTEINEN VERMITTELN

Title (fr)

IDENTIFICATION DE FACTEURS REGULANT L'INTERACTION ENTRE DES PROTEINES G HETEROTRIMERES ET DES PROTEINES G MONOMERES

Publication

EP 1064373 A2 (EN)

Application

EP 99912727 A

Priority

  • US 9906051 W
  • US 7863498 P

Abstract (en)

[origin: WO9947557A2] Monomeric GTPase guanine nucleotide exchange factor (GEF) have been identified which also contain an RGS region analogous to those of GTPase activating proteins (GAP). One of these GEF proteins, a Rho GEF has been demonstrated to contain an RGS sequence that has GAP activity toward a alpha subunit of a heterotrimeric G prote in.

IPC 1-7 (main, further and additional classification)

C12N 15/12; A61K 38/17; C07K 14/82; C12N 5/10; C12N 15/63; G01N 33/68

IPC 8 full level (invention and additional information)

C12N 15/09 (2006.01); C07K 14/00 (2006.01); C07K 14/47 (2006.01); C07K 14/82 (2006.01); C12N 5/10 (2006.01); C12N 9/16 (2006.01); C12Q 1/68 (2006.01)

CPC (invention and additional information)

C07K 14/82 (2013.01); C07K 14/4722 (2013.01); C12N 9/16 (2013.01)

Citation (search report)

See references of WO 9947557A3

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9947557 A2 19990923; WO 9947557 A3 19991118; AU 3103899 A 19991011; CA 2319037 A1 19990923; CN 1293709 A 20010502; EP 1064373 A2 20010103; JP 2002509862 A 20020402

INPADOC legal status


2005-04-27 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20041001

2003-05-14 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20030328

2001-01-03 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000828

2001-01-03 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE